Florinef and Restoril drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Florinef (fludrocortisone acetate) and Restoril (temazepam). Common drug interactions include renal failure acute among females and dizziness among males.

The phase IV clinical study analyzes what interactions people have when they take Florinef and Restoril. It is created by eHealthMe based on reports of 40 people who take the same drugs from the FDA, and is updated regularly.

What is Florinef?

Florinef has active ingredients of fludrocortisone acetate. It is often used in addison's disease. eHealthMe is studying from 3,834 Florinef users. Check the latest studies of Florinef.

What is Restoril?

Restoril has active ingredients of temazepam. It is often used in insomnia. eHealthMe is studying from 13,522 Restoril users. Check the latest studies of Restoril.

On Jul, 07, 2026

40 people who take Florinef and Restoril together, and have interactions are studied.

Florinef and Restoril drug interactions.

What are the common drug interactions of Florinef and Restoril, by gender? *:

female:

Renal failure acute (rapid kidney dysfunction)
Renal failure chronic (long lasting kidney dysfunction)
Respiratory failure (inadequate gas exchange by the respiratory system)
Syncope (loss of consciousness with an inability to maintain postural tone)
Thoracic haemorrhage (bleeding from chest cavity)
Anaemia (lack of blood)
Arthralgia (joint pain)
Arthropathy
Chills (felling of cold)
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)

male:

Dizziness
Chest pain
Pain in extremity
Rotator cuff syndrome (a spectrum of conditions affecting the rotator cuff tendons of the shoulder)
Sinus bradycardia (an unusually slow heartbeat due to heart disease)
Thrombosis (formation of a blood clot inside a blood vessel)
Traumatic haematoma (a blood clot in body due to trauma)
Varicose vein (veins that have become enlarged and tortuous)
Weight increased
Abdominal pain

What are the common drug interactions of Florinef and Restoril, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Anxiety
Back pain
Decreased appetite
Depression
Disturbance in attention
Hypoaesthesia (reduced sense of touch or sensation)
Memory impairment
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Oedema peripheral (superficial swelling)
Speech disorder

30-39:

Drug ineffective
Foot fracture
Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)

40-49:

Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Dyspnoea (difficult or laboured respiration)
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Dehydration (dryness resulting from the removal of water)
Depression
Ascites (accumulation of fluid in the abdominal cavity)
Asthenia (weakness)
Bacterial sepsis
Blindness
Chest pain

50-59:

Decreased appetite
Drug ineffective
Hyperaesthesia
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Pain in extremity
Red blood cell count decreased
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Dehydration (dryness resulting from the removal of water)
Vision blurred
Headache (pain in head)

60+:

Arthralgia (joint pain)
Headache (pain in head)
Cytomegalovirus colitis (an inflammation of the colon from virus)
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
Dizziness
Dyspnoea (difficult or laboured respiration)
Dystrophia myotonica (muscles are weak and are slow to relax after contraction)
Faecal occult blood positive
Gait disturbance
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)

What are the existing conditions these people have? *

Pain: 4 people, 10.00%
Weight Decreased: 3 people, 7.50%
Stress And Anxiety: 3 people, 7.50%
Constipation: 3 people, 7.50%
Hypotension (abnormally low blood pressure): 2 people, 5.00%
Behcet's Syndrome (involves inflammation of the blood vessels): 2 people, 5.00%
Depression: 2 people, 5.00%
Duodenitis (inflammation of the duodenum): 2 people, 5.00%
Electrolyte Imbalance: 2 people, 5.00%
Fever: 2 people, 5.00%

* Approximation only. Some reports may have incomplete information.

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