Flovent and Apresoline drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Flovent (fluticasone propionate) and Apresoline (hydralazine hydrochloride). Common drug interactions include chronic kidney disease among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Flovent and Apresoline. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Flovent?

Flovent has active ingredients of fluticasone propionate. It is often used in asthma. eHealthMe is studying from 44,817 Flovent users. Check the latest studies of Flovent.

What is Apresoline?

Apresoline has active ingredients of hydralazine hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 2,475 Apresoline users. Check the latest studies of Apresoline.

On Jul, 31, 2026

20 people who take Flovent and Apresoline together, and have interactions are studied.

Flovent and Apresoline drug interactions.

What are the common drug interactions of Flovent and Apresoline, by gender? *:

female:

Chronic kidney disease
Fall
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Myalgia (muscle pain)
Nephrogenic anaemia (anaemia due to kidney disease)
Abdominal pain upper
Diarrhoea
Hypoaesthesia (reduced sense of touch or sensation)
Nausea (feeling of having an urge to vomit)
Oedema (fluid collection in tissue)

male:

Fatigue (feeling of tiredness)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Extubation
Mitral valve stenosis (narrowing of mitral valve)
Ammonia increased
Aortic disorder
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Belligerence (aggressive or warlike behaviour)
Blood bilirubin increased
Blood creatinine increased

What are the common drug interactions of Flovent and Apresoline, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Endocarditis (inflammation in heart muscle)
Fatigue (feeling of tiredness)
Laryngomalacia (a congenital softening of the tissues of the larynx)
Pericardial effusion (fluid around the heart)
Pneumonia
Pulmonary embolism (blockage of the main artery of the lung)
Respiratory distress (difficulty in breathing)
Respiratory tract oedema (swelling of respiratory tract due to excess fluid collection in tissue)
Streptococcal bacteraemia (a bacterial infection of blood)

20-29:

n/a

30-39:

Chronic kidney disease
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Renal injury (kidney injury)

40-49:

Aortic disorder
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Bone disorder
Cardiac disorder
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Hand fracture
Osteoporosis (bones weak and more likely to break)
Spinal cord injury

50-59:

Cough
Ear discomfort
Euphoric mood (excessively happy but may become angry or irritable)
Pain in extremity
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Salivary hypersecretion (excess saliva secretion)
Somnolence (a state of near-sleep, a strong desire for sleep)
Throat irritation
Vomiting

60+:

Fall
Diarrhoea
Belligerence (aggressive or warlike behaviour)
Blood bilirubin increased
Blood creatinine increased
Blood glucose increased
Blood urea increased
Cardiac failure congestive
Cardiomegaly (increased size of heart than normal)
Chest pain

What are the existing conditions these people have? *

Hypersensitivity: 4 people, 20.00%
Cough: 3 people, 15.00%
Migraine (headache): 2 people, 10.00%
Pain: 2 people, 10.00%
Osteoporosis (bones weak and more likely to break): 2 people, 10.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 10.00%
Diabetes: 1 person, 5.00%
High Blood Cholesterol: 1 person, 5.00%
Heart Disease: 1 person, 5.00%
Gouty Arthritis (joint inflammation with crystal formation): 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

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