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Flovent and Hetlioz drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Flovent (fluticasone propionate) and Hetlioz (tasimelteon). Common drug interactions include mood altered among females and initial insomnia among males.

The phase IV clinical study analyzes what interactions people have when they take Flovent and Hetlioz. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Flovent?

Flovent has active ingredients of fluticasone propionate. It is often used in asthma. eHealthMe is studying from 44,817 Flovent users. Check the latest studies of Flovent.

What is Hetlioz?

Hetlioz has active ingredients of tasimelteon. eHealthMe is studying from 7,418 Hetlioz users. Check the latest studies of Hetlioz.

On Jul, 26, 2026

13 people who take Flovent and Hetlioz together, and have interactions are studied.

Flovent and Hetlioz drug interactions.

What are the common drug interactions of Flovent and Hetlioz, by gender? *:

female:

  1. Mood altered (changes in mood)
  2. Drug effect decreased
  3. Drug ineffective
  4. Hyperaesthesia
  5. Initial insomnia (feeling of inadequate or poor-quality sleep)
  6. Restlessness (not able to rest)
  7. Insomnia (sleeplessness)
  8. Food poisoning (poison in food)
  9. Nightmare (unpleasant dream)
  10. Depression

male:

  1. Initial insomnia (feeling of inadequate or poor-quality sleep)
  2. Insomnia (sleeplessness)
  3. Poor quality sleep
  4. Hypersensitivity
  5. Sinusitis (inflammation of sinus)
  6. Upper respiratory tract infection

What are the common drug interactions of Flovent and Hetlioz, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Initial insomnia (feeling of inadequate or poor-quality sleep)
  2. Insomnia (sleeplessness)
  3. Poor quality sleep

30-39:

  1. Drug ineffective

40-49:

n/a

50-59:

  1. Drug effect decreased
  2. Food poisoning (poison in food)
  3. Initial insomnia (feeling of inadequate or poor-quality sleep)
  4. Insomnia (sleeplessness)
  5. Nightmare (unpleasant dream)

60+:

  1. Upper respiratory tract infection

What are the existing conditions these people have? *

  1. Circadian Rhythm Sleep Disorder (family of sleep disorders affecting, among other things, the timing of sleep): 3 people, 23.08%
  2. Nightmares (unpleasant dreams): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Flovent and Hetlioz?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Flovent and Hetlioz:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Flovent:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Hetlioz:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Flovent and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Hetlioz and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on fluticasone propionate and tasimelteon (the active ingredients of Flovent and Hetlioz, respectively), and Flovent and Hetlioz (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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