Flovent and Pamelor drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Flovent (fluticasone propionate) and Pamelor (nortriptyline hydrochloride). Common drug interactions include hypoglycaemia among females and arthralgia among males.
The phase IV clinical study analyzes what interactions people have when they take Flovent and Pamelor. It is created by eHealthMe based on reports of 48 people who take the same drugs from the FDA, and is updated regularly.
What is Flovent?
Flovent has active ingredients of fluticasone propionate. It is often used in asthma. eHealthMe is studying from 44,817 Flovent users. Check the latest studies of Flovent.
What is Pamelor?
Pamelor has active ingredients of nortriptyline hydrochloride. It is often used in migraine. eHealthMe is studying from 4,069 Pamelor users. Check the latest studies of Pamelor.
48 people who take Flovent and Pamelor together, and have interactions are studied.

What are the common drug interactions of Flovent and Pamelor, by gender? *:
female:
- Hypoglycaemia (deficiency of glucose in the bloodstream)
- Muscular weakness (muscle weakness)
- Nausea (feeling of having an urge to vomit)
- Ovarian cyst ruptured (tear in fluid filled sac of the ovary)
- Pulmonary mass
- Surgery
- Vulvovaginal pain
- Anxiety
- Autoimmune disorder (a condition in which the immune system attacks the body's normal substances and tissue)
- Blood glucose increased
male:
- Arthralgia (joint pain)
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Delirium (wild excitement)
- Back pain
- Bone loss
- Cardiomegaly (increased size of heart than normal)
- Colonic polyp (extra part of colon tissue grow in intestine)
- Diarrhoea
- Drug toxicity
- Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
What are the common drug interactions of Flovent and Pamelor, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
- Drug administration error
20-29:
n/a
30-39:
- Hypoaesthesia (reduced sense of touch or sensation)
- Diarrhoea
- Vomiting
- Arthralgia (joint pain)
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Cardiomegaly (increased size of heart than normal)
- Delirium (wild excitement)
- Drug toxicity
- Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
- Dyspepsia (indigestion)
40-49:
- Pulmonary hypertension (increase in blood pressure in the lung artery)
- Drug dependence
- Fatigue (feeling of tiredness)
- Suicidal ideation
- Abdominal pain upper
- Affect lability (emotional incontinence)
- Agoraphobia (extreme or irrational fear of crowded spaces or enclosed public places)
- Arthralgia (joint pain)
- Asthenia (weakness)
- Bipolar disorder (mood disorder)
50-59:
- Dysuria (painful or difficult urination)
- Emotional distress
- Nephrolithiasis (calculi in the kidneys)
- Nerve injury
- Osteonecrosis (death of bone)
- Renal failure (kidney dysfunction)
- Tooth loss
- Arthralgia (joint pain)
- Drug resistance (reduction in effectiveness of a drug)
- Genotype drug resistance test positive
60+:
- Colonic polyp (extra part of colon tissue grow in intestine)
- Hypoaesthesia (reduced sense of touch or sensation)
- Atelectasis (partial or complete collapse of the lung)
- Back pain
- Benign prostatic hyperplasia (benign enlargement of the prostate)
- Bone disorder
- Bone erosion
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Cataract (clouding of the lens inside the eye)
- Cerebral atrophy (decrement in size of brain)
What are the existing conditions these people have? *
- Pain: 14 people, 29.17%
- Nausea (feeling of having an urge to vomit): 10 people, 20.83%
- Depression: 8 people, 16.67%
- Muscle Spasms (muscle contraction): 7 people, 14.58%
- Oral Pain: 5 people, 10.42%
- Oedema (fluid collection in tissue): 5 people, 10.42%
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 10.42%
- Multiple Myeloma (cancer of the plasma cells): 5 people, 10.42%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 10.42%
- Cough: 5 people, 10.42%
* Approximation only. Some reports may have incomplete information.
Do you take Flovent and Pamelor?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Flovent and Pamelor:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Flovent:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Pamelor:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Flovent and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Pamelor and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Lehrer, S., & Rheinstein, P. H. , "Alzheimer’s Disease and Intranasal Fluticasone Propionate in the FDA MedWatch Adverse Events Database", Journal of Alzheimer's disease reports, (Preprint), 1-5., 2018 Jan .
- Lehrer, S., & Rheinstein, P. H. , "Alzheimer’s Disease and Intranasal Fluticasone Propionate in the FDA MedWatch Adverse Events Database", Journal of Alzheimer's disease reports, (Preprint), 1-5., 2018 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on fluticasone propionate and nortriptyline hydrochloride (the active ingredients of Flovent and Pamelor, respectively), and Flovent and Pamelor (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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