Flovent and Phytonadione drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Flovent (fluticasone propionate) and Phytonadione (phytonadione). Common drug interactions include platelet count decreased among females and infective pulmonary exacerbation of cystic fibrosis among males.

The phase IV clinical study analyzes what interactions people have when they take Flovent and Phytonadione. It is created by eHealthMe based on reports of 59 people who take the same drugs from the FDA, and is updated regularly.

What is Flovent?

Flovent has active ingredients of fluticasone propionate. It is often used in asthma. eHealthMe is studying from 44,817 Flovent users. Check the latest studies of Flovent.

What is Phytonadione?

Phytonadione has active ingredients of phytonadione. It is often used in hemorrhagic stroke. eHealthMe is studying from 2,870 Phytonadione users. Check the latest studies of Phytonadione.



On Jul, 17, 2026

59 people who take Flovent and Phytonadione together, and have interactions are studied.

Flovent and Phytonadione drug interactions.

What are the common drug interactions of Flovent and Phytonadione, by gender? *:

female:

  1. Platelet count decreased
  2. Post procedural haemorrhage (post procedural bleeding)
  3. Pulmonary function test decreased
  4. Renal failure (kidney dysfunction)
  5. Sinusitis (inflammation of sinus)
  6. Splenomegaly (enlargement of spleen)
  7. Tachypnoea (a condition of rapid breathing over 20 per minute)
  8. Vitamin k deficiency
  9. Weight decreased
  10. Acute hepatic failure

male:

  1. Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
  2. Blood pressure decreased
  3. Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
  4. Clubbing (deformity of the fingers and fingernails)
  5. Cough
  6. Cystic fibrosis related diabetes
  7. Decreased appetite
  8. Diarrhoea
  9. Distal intestinal obstruction syndrome (blockage of the intestines by thickened stool and occurs in individuals with cystic fibrosis)
  10. Dizziness

What are the common drug interactions of Flovent and Phytonadione, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Biliary dilatation
  2. Biliary tract disorder
  3. Bilirubin conjugated increased
  4. Blood alkaline phosphatase increased
  5. Blood bilirubin increased
  6. Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection)
  7. Cholangitis (infection of the bile duct)
  8. Chronic hepatic failure (long lasting liver failure)
  9. Constipation
  10. Deficiency of bile secretion

10-19:

  1. Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
  2. Cystic fibrosis (disease of the secretary glands)
  3. Lung disorder (lung disease)
  4. Pneumonia
  5. Sinusitis (inflammation of sinus)
  6. Aspartate aminotransferase increased
  7. Dyspnoea (difficult or laboured respiration)
  8. Hospitalisation
  9. Infection
  10. Pulmonary function test decreased

20-29:

  1. Abdominal pain
  2. Blood pressure decreased
  3. Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection)
  4. Chest discomfort
  5. Chest pain
  6. Chills (felling of cold)
  7. Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
  8. Clubbing (deformity of the fingers and fingernails)
  9. Cough
  10. Cystic fibrosis (disease of the secretary glands)

30-39:

n/a

40-49:

n/a

50-59:

  1. Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
  2. Dry skin
  3. Erythema (redness of the skin)
  4. Face oedema (swelling of face)
  5. Pruritus (severe itching of the skin)

60+:

  1. Left ventricular dysfunction
  2. Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood)
  3. Respiratory distress (difficulty in breathing)
  4. Respiratory failure (inadequate gas exchange by the respiratory system)
  5. Sepsis (a severe blood infection that can lead to organ failure and death)
  6. Coronary artery occlusion (complete obstruction of blood flow in a coronary artery)
  7. Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
  8. Blood pressure decreased
  9. Chest pain
  10. Thrombocytopenia (decrease of platelets in blood)

What are the existing conditions these people have? *

  1. Cystic Fibrosis (disease of the secretary glands): 40 people, 67.80%
  2. Pain: 8 people, 13.56%
  3. Pseudomonas Infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa): 6 people, 10.17%
  4. Multiple Myeloma (cancer of the plasma cells): 6 people, 10.17%
  5. Obstructive Airways Disorder (a progressive disease that makes it hard to breathe): 5 people, 8.47%
  6. Seasonal Allergy (allergic condition due to certain season): 4 people, 6.78%
  7. Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking): 4 people, 6.78%
  8. Diabetes: 4 people, 6.78%
  9. Cystic Fibrosis Lung (fibrosis with cyst in the lung): 4 people, 6.78%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Flovent and Phytonadione:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Flovent:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Phytonadione:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Flovent and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Phytonadione and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on fluticasone propionate and phytonadione (the active ingredients of Flovent and Phytonadione, respectively), and Flovent and Phytonadione (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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