Flovent and Tezspire drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Flovent (fluticasone propionate) and Tezspire (tezepelumab-ekko). Common drug interactions include wheezing among females and back pain among males.

The phase IV clinical study analyzes what interactions people have when they take Flovent and Tezspire. It is created by eHealthMe based on reports of 29 people who take the same drugs from the FDA, and is updated regularly.

What is Flovent?

Flovent has active ingredients of fluticasone propionate. It is often used in asthma. eHealthMe is studying from 44,817 Flovent users. Check the latest studies of Flovent.

What is Tezspire?

Tezspire has active ingredients of tezepelumab-ekko. eHealthMe is studying from 2,353 Tezspire users. Check the latest studies of Tezspire.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 29, 2026

29 people who take Flovent and Tezspire together, and have interactions are studied.

Flovent and Tezspire drug interactions.

What are the common drug interactions of Flovent and Tezspire, by gender? *:

female:

  1. Wheezing (a high-pitched whistling sound made while you breath)
  2. Sleep disorder due to a general medical condition
  3. Cough
  4. Pneumonia
  5. Multiple allergies (allergy to multiple agents)
  6. Peripheral swelling
  7. Back pain
  8. Cataract (clouding of the lens inside the eye)
  9. Chest discomfort
  10. Heart rate decreased

male:

  1. Back pain
  2. Chest discomfort
  3. Malaise (a feeling of general discomfort or uneasiness)
  4. Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
  5. Pain
  6. Pneumonia
  7. Pneumonitis (inflammation of the walls of the alveoli in the lungs)
  8. Pulmonary congestion (congestion in the lungs)
  9. Respiratory tract irritation

What are the common drug interactions of Flovent and Tezspire, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Abdominal distension
  2. Atelectasis (partial or complete collapse of the lung)
  3. Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection)
  4. Chest discomfort
  5. Chest pain
  6. Choking (mechanical obstruction of the flow of air from the environment into the lungs)
  7. Cough
  8. Drug ineffective
  9. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  10. Hypertension (high blood pressure)

60+:

  1. Cough
  2. Multiple allergies (allergy to multiple agents)
  3. Pulmonary congestion (congestion in the lungs)
  4. Abdominal pain
  5. Abdominal pain upper
  6. Arthralgia (joint pain)
  7. Blepharitis (chronic inflammation of the eyelid)
  8. Catheter site pain
  9. Chest discomfort
  10. Chills (felling of cold)

What are the existing conditions these people have? *

  1. Immunodeficiency Common Variable: 3 people, 10.34%

* Approximation only. Some reports may have incomplete information.

Do you take Flovent and Tezspire?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Flovent and Tezspire:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Flovent:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Tezspire:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Flovent and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Tezspire and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on fluticasone propionate and tezepelumab-ekko (the active ingredients of Flovent and Tezspire, respectively), and Flovent and Tezspire (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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