Floxin and Avelox drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Floxin (ofloxacin) and Avelox (moxifloxacin hydrochloride). Common drug interactions include emotional distress among females and amnesia among males.

The phase IV clinical study analyzes what interactions people have when they take Floxin and Avelox. It is created by eHealthMe based on reports of 41 people who take the same drugs from the FDA, and is updated regularly.

What is Floxin?

Floxin has active ingredients of ofloxacin. eHealthMe is studying from 1,737 Floxin users. Check the latest studies of Floxin.

What is Avelox?

Avelox has active ingredients of moxifloxacin hydrochloride. It is often used in sinusitis. eHealthMe is studying from 28,651 Avelox users. Check the latest studies of Avelox.



On Jul, 07, 2026

41 people who take Floxin and Avelox together, and have interactions are studied.

Floxin and Avelox drug interactions.

What are the common drug interactions of Floxin and Avelox, by gender? *:

female:

  1. Emotional distress
  2. Facial pain
  3. Fatigue (feeling of tiredness)
  4. Injury
  5. Myalgia (muscle pain)
  6. Myositis (inflammation of the muscles)
  7. Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
  8. Nausea (feeling of having an urge to vomit)
  9. Neuropathy peripheral (surface nerve damage)
  10. Oedema peripheral (superficial swelling)

male:

  1. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  2. Anaemia (lack of blood)
  3. Chest discomfort
  4. Chest pain
  5. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  6. Cough
  7. Dehydration (dryness resulting from the removal of water)
  8. Depression
  9. Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
  10. Dizziness

What are the common drug interactions of Floxin and Avelox, by age (0-1 to 60+)? *:

0-1:

  1. Anxiety
  2. Asthma
  3. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  4. Fungal infection
  5. Pyrexia (fever)
  6. Stomatitis (inflammation of mucous membrane of mouth)

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Asthenia (weakness)
  2. Back pain
  3. Dyspnoea (difficult or laboured respiration)
  4. Nausea (feeling of having an urge to vomit)
  5. Anxiety
  6. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  7. Burning sensation
  8. Cough
  9. Depression
  10. Emotional distress

40-49:

  1. Dyspnoea (difficult or laboured respiration)
  2. Hyperlipidaemia (presence of excess lipids in the blood)
  3. Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
  4. Urinary tract infection
  5. Abdominal pain
  6. Blood cholesterol increased
  7. Cardiac murmur (an heart sound in valve abnormality)
  8. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  9. Dehydration (dryness resulting from the removal of water)
  10. Dermal cyst

50-59:

  1. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  2. Anxiety
  3. Chronic kidney disease
  4. Depression
  5. Neuropathy peripheral (surface nerve damage)
  6. Peripheral sensorimotor neuropathy (damage to one or more of your peripheral nerves)
  7. Renal failure (kidney dysfunction)

60+:

  1. Asthenia (weakness)
  2. Cardiomegaly (increased size of heart than normal)
  3. Osteoarthritis (a joint disease caused by cartilage loss in a joint)
  4. Pain in extremity
  5. Abdominal discomfort
  6. Abdominal pain
  7. Abnormal faeces (abnormal stool)
  8. Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood)
  9. Agitation (state of anxiety or nervous excitement)
  10. Anaemia (lack of blood)

What are the existing conditions these people have? *

  1. Depression: 9 people, 21.95%
  2. Hallucination, Auditory (perceiving sounds without auditory stimulus): 8 people, 19.51%
  3. Bipolar Disorder (mood disorder): 8 people, 19.51%
  4. Pain: 4 people, 9.76%
  5. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 9.76%
  6. Otitis (ear infection): 3 people, 7.32%

* Approximation only. Some reports may have incomplete information.

Do you take Floxin and Avelox?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Floxin and Avelox:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Floxin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Avelox:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Floxin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Avelox and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on ofloxacin and moxifloxacin hydrochloride (the active ingredients of Floxin and Avelox, respectively), and Floxin and Avelox (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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