Floxin and Metronidazole drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Floxin (ofloxacin) and Metronidazole (metronidazole). Common drug interactions include paranoia among females and dyspnoea among males.

The phase IV clinical study analyzes what interactions people have when they take Floxin and Metronidazole. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Floxin?

Floxin has active ingredients of ofloxacin. eHealthMe is studying from 1,737 Floxin users. Check the latest studies of Floxin.

What is Metronidazole?

Metronidazole has active ingredients of metronidazole. It is often used in vaginitis bacterial. eHealthMe is studying from 59,578 Metronidazole users. Check the latest studies of Metronidazole.

On Aug, 10, 2026

27 people who take Floxin and Metronidazole together, and have interactions are studied.

Floxin and Metronidazole drug interactions.

What are the common drug interactions of Floxin and Metronidazole, by gender? *:

female:

Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur)
Agitation (state of anxiety or nervous excitement)
Blood pressure increased
Blood sodium increased
Drug hypersensitivity
Hallucination (an experience involving the perception of something not present)
Insomnia (sleeplessness)
Oesophageal reflux (moving the food downwards)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Pulmonary hypertension primary (increase in blood pressure in the lung artery with no cause)

male:

Dyspnoea (difficult or laboured respiration)
Syncope (loss of consciousness with an inability to maintain postural tone)
Chest pain
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Colitis (inflammation of colon)
Constipation
Cough
Dehydration (dryness resulting from the removal of water)
Electrocardiogram st-t change
Fall

What are the common drug interactions of Floxin and Metronidazole, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur)
Tremor (trembling or shaking movements in one or more parts of your body)
Anxiety
Confusion
Insomnia (sleeplessness)
Agitation (state of anxiety or nervous excitement)
Hallucination (an experience involving the perception of something not present)
Neurosis (a class of functional mental disorders involving distress but neither delusions nor hallucinations)
Suicide attempt

30-39:

Dyspnoea (difficult or laboured respiration)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
Cardiac murmur (an heart sound in valve abnormality)
Palpitations (feelings or sensations that your heart is pounding or racing)
Oedema lower limb (fluid collection in tissue of lower leg)
Blood pressure increased
Blood sodium increased
Cardiomegaly (increased size of heart than normal)
Chest pain

40-49:

Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Arrhythmia (irregular heartbeat)
Cerebrovascular disorder (disease of brain)
Death
Maternal exposure during pregnancy (use of substance during pregnancy)
Talipes

50-59:

Mucosal inflammation (infection of mucous membrane)
Pain
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Photophobia (extreme sensitivity to light)
Pneumonia
Pyrexia (fever)
Rash erythematous (redness of the skin)
Sepsis (a severe blood infection that can lead to organ failure and death)
Stevens johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
Tongue oedema (swelling of tongue)

60+:

Chest pain
Loss of consciousness
Cerebral atrophy (decrement in size of brain)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Colitis (inflammation of colon)
Colonic polyp (extra part of colon tissue grow in intestine)
Constipation
Cough
Dehydration (dryness resulting from the removal of water)
Dyspnoea (difficult or laboured respiration)

* Approximation only. Some reports may have incomplete information.

Do you take Floxin and Metronidazole?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously