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Fluconazole and Amifostine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Fluconazole (fluconazole) and Amifostine (amifostine). Common drug interactions include bone disorder among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Fluconazole and Amifostine. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Fluconazole?

Fluconazole has active ingredients of fluconazole. It is often used in vaginal yeast infection. eHealthMe is studying from 70,481 Fluconazole users. Check the latest studies of Fluconazole.

What is Amifostine?

Amifostine has active ingredients of amifostine. eHealthMe is studying from 425 Amifostine users. Check the latest studies of Amifostine.

On Jul, 20, 2026

21 people who take Fluconazole and Amifostine together, and have interactions are studied.

Fluconazole and Amifostine drug interactions.

What are the common drug interactions of Fluconazole and Amifostine, by gender? *:

female:

  1. Bone disorder
  2. Cardiomegaly (increased size of heart than normal)
  3. Discomfort
  4. Ear pain
  5. Emotional distress
  6. Hypertension (high blood pressure)
  7. Injury
  8. Mastication disorder (disease of chewing food)
  9. Nausea (feeling of having an urge to vomit)
  10. Neuropathy peripheral (surface nerve damage)

male:

  1. Anaemia (lack of blood)
  2. Febrile neutropenia (fever with reduced white blood cells)
  3. Mucosal inflammation (infection of mucous membrane)
  4. Thrombocytopenia (decrease of platelets in blood)
  5. Nausea (feeling of having an urge to vomit)
  6. Vomiting

What are the common drug interactions of Fluconazole and Amifostine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Cardiomegaly (increased size of heart than normal)
  2. Cough
  3. Discomfort
  4. Ear pain
  5. Emotional distress
  6. Fistula (an abnormal connection or passageway between two)
  7. Flank pain (a distressing sensation experienced around the lower back and the upper abdomen)
  8. Haematoma (collection of blood outside the blood vessels)
  9. Headache (pain in head)
  10. Hyperkeratosis (thickening of the outer layer of the skin)

60+:

  1. Full blood count decreased
  2. Hyperbilirubinaemia (excess of bilirubin in the blood)
  3. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 14 people, 66.67%
  2. Non-Hodgkin's Lymphoma Recurrent (reoccurrence malignant (cancer) cells form in the lymph system): 4 people, 19.05%
  3. Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 2 people, 9.52%

* Approximation only. Some reports may have incomplete information.

Do you take Fluconazole and Amifostine?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Fluconazole and Amifostine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Fluconazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Amifostine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Fluconazole and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Amifostine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on fluconazole and amifostine (the active ingredients of Fluconazole and Amifostine, respectively), and Fluconazole and Amifostine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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