Fluconazole and Cabometyx drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Fluconazole (fluconazole) and Cabometyx (cabozantinib s-malate). Common drug interactions include blister among females and stomatitis among males.

The phase IV clinical study analyzes what interactions people have when they take Fluconazole and Cabometyx. It is created by eHealthMe based on reports of 86 people who take the same drugs from the FDA, and is updated regularly.

What is Fluconazole?

Fluconazole has active ingredients of fluconazole. It is often used in vaginal yeast infection. eHealthMe is studying from 70,481 Fluconazole users. Check the latest studies of Fluconazole.

What is Cabometyx?

Cabometyx has active ingredients of cabozantinib s-malate. eHealthMe is studying from 35,069 Cabometyx users. Check the latest studies of Cabometyx.

On Jul, 12, 2026

86 people who take Fluconazole and Cabometyx together, and have interactions are studied.

Fluconazole and Cabometyx drug interactions.

What are the common drug interactions of Fluconazole and Cabometyx, by gender? *:

female:

Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Blood pressure increased
Muscle spasms (muscle contraction)
Pain
Vomiting
Stomatitis (inflammation of mucous membrane of mouth)
Hypertension (high blood pressure)
White blood cell count decreased
Abdominal discomfort
Abdominal pain upper

male:

Stomatitis (inflammation of mucous membrane of mouth)
Decreased appetite
Headache (pain in head)
Malignant neoplasm progression (cancer tumour came back)
Asthenia (weakness)
Abdominal discomfort
Blood potassium decreased
Blood pressure fluctuation
Blood thyroid stimulating hormone increased
Dehydration (dryness resulting from the removal of water)

What are the common drug interactions of Fluconazole and Cabometyx, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Malignant neoplasm progression (cancer tumour came back)
Septic shock (shock due to blood infection)

20-29:

Alanine aminotransferase increased
Anxiety
Aspartate aminotransferase increased
Blood bilirubin increased
Cancer pain
Dyspnoea exertional (breathlessness or shortness of breath)
Gallbladder disorder
Hypoaesthesia oral (reduced sense of touch or sensation in mouth)
Metastases to lung (cancer spreads to lung)
Pericardial effusion (fluid around the heart)

30-39:

n/a

40-49:

Acute respiratory failure
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Constipation
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Glioblastoma multiforme (most common and deadliest of malignant primary brain tumours in adults)
Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
Post procedural infection
Pulmonary embolism (blockage of the main artery of the lung)
Pulmonary haemorrhage (acute bleeding from the lung)
Rash

50-59:

Anaemia (lack of blood)
Body tinea (ringworm of the body)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Genital infection fungal
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Hair colour changes
Helicobacter gastritis (inflammation of the inner lining of the stomach caused by helicobacter pylori (h. pylori) a bacterium)
Helicobacter infection (helicobacter pylori (h. pylori) infects stomach)
Muscle spasms (muscle contraction)
Pain in extremity

60+:

Malignant neoplasm progression (cancer tumour came back)
Stomatitis (inflammation of mucous membrane of mouth)
Dysphonia (speech disorder attributable to a disorder of phonation)
Genital rash (rash on sex organ)
Palmar-plantar erythrodysaesthesia syndrome (hand-foot syndrome)
Rash
Retroperitoneal haemorrhage (bleeding between the peritoneum and the posterior abdominal wall)
Seasonal allergy (allergic condition due to certain season)
Fatigue (feeling of tiredness)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)

What are the existing conditions these people have? *

Renal Cell Carcinoma (a kidney cancer): 71 people, 82.56%

* Approximation only. Some reports may have incomplete information.

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