Fluconazole and Midostaurin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Fluconazole (fluconazole) and Midostaurin (midostaurin). Common drug interactions include nausea among females and septic shock among males.

The phase IV clinical study analyzes what interactions people have when they take Fluconazole and Midostaurin. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Fluconazole?

Fluconazole has active ingredients of fluconazole. It is often used in vaginal yeast infection. eHealthMe is studying from 70,481 Fluconazole users. Check the latest studies of Fluconazole.

What is Midostaurin?

Midostaurin has active ingredients of midostaurin. eHealthMe is studying from 1,137 Midostaurin users. Check the latest studies of Midostaurin.

On Jul, 26, 2026

12 people who take Fluconazole and Midostaurin together, and have interactions are studied.

Fluconazole and Midostaurin drug interactions.

What are the common drug interactions of Fluconazole and Midostaurin, by gender? *:

female:

Nausea (feeling of having an urge to vomit)
Vomiting
Haemoglobin decreased
Klebsiella sepsis (klebsiella causes a potentially fatal whole-body inflammation)
Platelet count decreased
Pneumonia klebsiella (pneumonia caused by bacteria klebsiella)
Staphylococcal infection (an infection with staphylococcus bacteria)
Streptococcal sepsis (whole body inflammation by streptococcal)
White blood cell count decreased
Abdominal pain

male:

Septic shock (shock due to blood infection)
Dysplasia (enlargement of an organ or tissue)
Skin infection
Thrombocytopenia (decrease of platelets in blood)
Acute febrile neutrophilic dermatosis (skin disease characterized by the sudden onset of fever, leukocytosis, and tender)
Drug level increased
Multi-organ disorder (multiple organ disease)
Sepsis (a severe blood infection that can lead to organ failure and death)
Febrile neutropenia (fever with reduced white blood cells)
Haemoglobin decreased

What are the common drug interactions of Fluconazole and Midostaurin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Diarrhoea
Nausea (feeling of having an urge to vomit)
Vomiting

40-49:

Hallucination, visual (seeing things that aren't there)

50-59:

Vomiting
White blood cell count decreased
Dysplasia (enlargement of an organ or tissue)
Febrile neutropenia (fever with reduced white blood cells)
Neutropenia (an abnormally low number of neutrophils)
Pain
Pain in extremity
Pruritus (severe itching of the skin)
Septic shock (shock due to blood infection)
Skin infection

60+:

Immunosuppressant drug level increased
Acute febrile neutrophilic dermatosis (skin disease characterized by the sudden onset of fever, leukocytosis, and tender)
Drug level increased

What are the existing conditions these people have? *

Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 10 people, 83.33%
Systemic Mastocytosis (a condition caused by the accumulation of mast cells in more than one part of the body): 1 person, 8.33%
Sepsis (a severe blood infection that can lead to organ failure and death): 1 person, 8.33%
Pneumonia: 1 person, 8.33%
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 1 person, 8.33%
Nausea And Vomiting: 1 person, 8.33%
Multiple Myeloma (cancer of the plasma cells): 1 person, 8.33%
Immunodeficiency Disorders: 1 person, 8.33%
Febrile Neutropenia (fever with reduced white blood cells): 1 person, 8.33%
Diarrhea: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

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