Fluconazole and Ofirmev drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Fluconazole (fluconazole) and Ofirmev (acetaminophen). Common drug interactions include burning sensation among females and alanine aminotransferase increased among males.

The phase IV clinical study analyzes what interactions people have when they take Fluconazole and Ofirmev. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Fluconazole?

Fluconazole has active ingredients of fluconazole. It is often used in vaginal yeast infection. eHealthMe is studying from 70,481 Fluconazole users. Check the latest studies of Fluconazole.

What is Ofirmev?

Ofirmev has active ingredients of acetaminophen. eHealthMe is studying from 817 Ofirmev users. Check the latest studies of Ofirmev.

On Aug, 06, 2026

13 people who take Fluconazole and Ofirmev together, and have interactions are studied.

Fluconazole and Ofirmev drug interactions.

What are the common drug interactions of Fluconazole and Ofirmev, by gender? *:

female:

Burning sensation
Erythema (redness of the skin)
Pruritus (severe itching of the skin)
Skin hyperpigmentation (disorders affect the colour of your skin)
Skin lesion
Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Ankle fracture
Anxiety
Aspartate aminotransferase increased

male:

Alanine aminotransferase increased
Aspartate aminotransferase increased
Staphylococcal bacteraemia (a bacterial infection of blood)
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
Acute lymphocytic leukaemia recurrent (cancer in which the bone marrow makes too many lymphocytes-recurrent)
Body temperature increased
Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Gamma-glutamyltransferase increased
Hypertransaminasaemia
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)

What are the common drug interactions of Fluconazole and Ofirmev, by age (0-1 to 60+)? *:

0-1:

Gamma-glutamyltransferase increased
Hypertransaminasaemia

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Burning sensation
Erythema (redness of the skin)
Pruritus (severe itching of the skin)
Skin hyperpigmentation (disorders affect the colour of your skin)
Skin lesion
Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)

50-59:

Aspartate aminotransferase increased
Blood bilirubin increased
Alanine aminotransferase increased
Chronic kidney disease
Dizziness
Fatigue (feeling of tiredness)
Hyperhidrosis (abnormally increased sweating)
Renal failure (kidney dysfunction)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)

60+:

Alanine aminotransferase increased
Aspartate aminotransferase increased
Pain
Osteonecrosis (death of bone)
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Ankle fracture
Anxiety
Bone density decreased
Bone loss

What are the existing conditions these people have? *

Pain: 4 people, 30.77%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 23.08%
Skin Blushing/flushing (a sudden reddening of the face, neck): 2 people, 15.38%
High Blood Pressure: 2 people, 15.38%
Cancer Pain: 2 people, 15.38%
Constipation: 2 people, 15.38%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 2 people, 15.38%
Dehydration (dryness resulting from the removal of water): 2 people, 15.38%
Drug Eruption (adverse drug reaction of the skin): 2 people, 15.38%
Essential Hypertension (primary hypertension): 2 people, 15.38%

* Approximation only. Some reports may have incomplete information.

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