Fluconazole and Rimifon drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Fluconazole (fluconazole) and Rimifon (isoniazid). Common drug interactions include agranulocytosis among females and hepatitis fulminant among males.

The phase IV clinical study analyzes what interactions people have when they take Fluconazole and Rimifon. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Fluconazole?

Fluconazole has active ingredients of fluconazole. It is often used in vaginal yeast infection. eHealthMe is studying from 70,481 Fluconazole users. Check the latest studies of Fluconazole.

What is Rimifon?

Rimifon has active ingredients of isoniazid. eHealthMe is studying from 925 Rimifon users. Check the latest studies of Rimifon.

On Jul, 04, 2026

21 people who take Fluconazole and Rimifon together, and have interactions are studied.

Fluconazole and Rimifon drug interactions.

What are the common drug interactions of Fluconazole and Rimifon, by gender? *:

female:

Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
Eosinophilia (eosinophil count in the peripheral blood exceeds)
Pruritus (severe itching of the skin)
Vomiting
Erythema (redness of the skin)
Liver disorder (liver diseases)
Pyrexia (fever)
Decreased appetite
Haematemesis (vomiting of blood)
Liver injury

male:

Hepatitis fulminant (life-threatening condition defined by significantly impaired liver function)
Peripheral ischaemia (impaired circulation to an extremity)
Central line infection (infection by central line in icu)
Citrobacter infection (infection by citrobacter (bacteria))
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Cryptococcosis (potentially fatal fungal disease)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Hepatocellular damage (liver damage)
Hiv infection
Hyperbilirubinaemia (excess of bilirubin in the blood)

What are the common drug interactions of Fluconazole and Rimifon, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Hepatitis fulminant (life-threatening condition defined by significantly impaired liver function)
Prothrombin time ratio decreased

30-39:

n/a

40-49:

Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
Eosinophilia (eosinophil count in the peripheral blood exceeds)
Pruritus (severe itching of the skin)
Vomiting
Erythema (redness of the skin)
Liver disorder (liver diseases)
Peripheral ischaemia (impaired circulation to an extremity)
Aortic thrombosis (formation of a blood clot inside aorta)
Decreased appetite
Haematemesis (vomiting of blood)

50-59:

Anaemia (lack of blood)
Anuria (failure of the kidneys to produce urine)
Central line infection (infection by central line in icu)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Hepatitis fulminant (life-threatening condition defined by significantly impaired liver function)
Lung infection
Septic shock (shock due to blood infection)
Serratia infection (bacterial infection)

60+:

Hepatitis fulminant (life-threatening condition defined by significantly impaired liver function)
Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
Pain in limb
Peripheral neuropathy (damage to nerves of the peripheral nervous system)
Pyrexia (fever)
Blood lactate dehydrogenase increased
Cryptococcosis (potentially fatal fungal disease)
Drug ineffective
Hepatitis (inflammation of the liver)
Hepatocellular damage (liver damage)

What are the existing conditions these people have? *

Cryptococcosis (potentially fatal fungal disease): 8 people, 38.10%
Hiv Infection: 7 people, 33.33%
Disseminated Tuberculosis: 3 people, 14.29%
Tuberculosis (a bacterial infection by mycobacterium tuberculosis): 2 people, 9.52%

* Approximation only. Some reports may have incomplete information.

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