Fluconazole and Simulect drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Fluconazole (fluconazole) and Simulect (basiliximab). Common drug interactions include acute coronary syndrome among females and haemoglobin decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Fluconazole and Simulect. It is created by eHealthMe based on reports of 78 people who take the same drugs from the FDA, and is updated regularly.

What is Fluconazole?

Fluconazole has active ingredients of fluconazole. It is often used in vaginal yeast infection. eHealthMe is studying from 70,481 Fluconazole users. Check the latest studies of Fluconazole.

What is Simulect?

Simulect has active ingredients of basiliximab. eHealthMe is studying from 3,861 Simulect users. Check the latest studies of Simulect.

On Jul, 11, 2026

78 people who take Fluconazole and Simulect together, and have interactions are studied.

Fluconazole and Simulect drug interactions.

What are the common drug interactions of Fluconazole and Simulect, by gender? *:

female:

Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood)
Brain natriuretic peptide increased
Cardiotoxicity (damage to the heart muscle)
Coronary artery stenosis (narrowing of coronary artery)
Diabetic macroangiopathy (fat and blood clots build up in the large blood vessels due to diabetes)
Electrocardiogram st segment depression
Escherichia urinary tract infection (urinary tract infection by escherichia coli)
Extremity necrosis (death of body tissue of arms and legs)
Hypotonia (low muscle tone)
Inflammation

male:

Haemoglobin decreased
Hyperkalaemia (damage to or disease of the kidney)
Vomiting
Acute graft versus host disease (acute complication following an allogeneic tissue/blood transplant)
Kidney transplant rejection
Pseudomonas infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa)
Urinary tract infection
Abdominal pain
Complications of transplanted kidney
Dysphagia (a condition in which swallowing is difficult or painful)

What are the common drug interactions of Fluconazole and Simulect, by age (0-1 to 60+)? *:

0-1:

Aspergillosis (an infection caused by a fungus called aspergillus)
Bile duct obstruction (blockage in the tubes that carry bile from the liver to the gallbladder)
Fungal endocarditis (fungal infection of the inner layer of the heart)
Oxygen saturation decreased
Pleural effusion (water on the lungs)
Pyrexia (fever)
Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)

2-9:

Pyrexia (fever)
Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)
Acute respiratory distress syndrome
C-reactive protein increased
Non-cardiogenic pulmonary oedema (protein and fluid accumulation in the alveoli without pulmonary capillary pressure)
Respiratory failure (inadequate gas exchange by the respiratory system)

10-19:

Chronic graft versus host disease in skin (damage by immune cells to skin after grafting)
Cystitis haemorrhagic (blood in the urine and painful voiding)
Gastrointestinal infection (infection of stomach and intestine)
Pyrexia (fever)
Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)

20-29:

Cytomegalovirus viraemia (cytomegalo virus in blood stream)
Procedural pain
Abdominal pain
Decreased appetite
Diarrhoea
Nausea (feeling of having an urge to vomit)
Vomiting
Focal glomerulosclerosis (disease that attacks the kidney's filtering system (glomeruli) causing serious scarring)
Hyperkalaemia (damage to or disease of the kidney)
Renal impairment (severely reduced kidney function)

30-39:

Kidney transplant rejection
Cytomegalovirus test positive
Pancreatic leak
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Renal impairment (severely reduced kidney function)
Glomerulonephritis (a group of conditions that affect parts of the kidneys called glomeruli)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Cytomegalovirus infection
Haemoglobin decreased
Pneumonia

40-49:

Acute graft versus host disease (acute complication following an allogeneic tissue/blood transplant)
Cystitis haemorrhagic (blood in the urine and painful voiding)
Stomatitis (inflammation of mucous membrane of mouth)
Enteritis (inflammation of the small intestine)
Guillain-barre syndrome (the body's immune system attacks its peripheral nervous system)
Interstitial lung disease
Plasma cell myeloma (cancer that begins in plasma cells)
Pneumonia
Urinary tract infection
Neutropenia (an abnormally low number of neutrophils)

50-59:

Disseminated intravascular coagulation (systemic activation of blood coagulation)
Enterococcal infection
Flatulence (flatus expelled through the anus)
Haemolysis (breaking open of red blood cells and the release of haemoglobin into the surrounding fluid)
Haemolytic uraemic syndrome (blood clotting disease caused by e. coli infection, birth control pills, pneumonia, medications, and more)
Haemorrhage (bleeding)
Hepatic failure (liver failure)
Hepatic necrosis (large portions of liver die off due to severe liver disease)
Hepatorenal syndrome (renal failure in patients with advanced chronic liver disease)
Inflammatory marker increased

60+:

Sepsis (a severe blood infection that can lead to organ failure and death)
Cardiac arrest
Nausea (feeling of having an urge to vomit)
Non-cardiac chest pain
Oesophageal candidiasis (fungal infection of oesophagus)
Oral candidiasis (fungal infection of mouth)
Septic shock (shock due to blood infection)
Urinary tract infection enterococcal
Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)

What are the existing conditions these people have? *

Sedation: 21 people, 26.92%
Immunodeficiency Disorders: 15 people, 19.23%
C-Reactive Protein Increased: 15 people, 19.23%
Immune Tolerance Induction: 11 people, 14.10%
Cardiac Disorder: 10 people, 12.82%
Urinary Tract Infection: 8 people, 10.26%
Bone Marrow Conditioning Regimen: 8 people, 10.26%
Acute Coronary Syndrome (acute chest pain and other symptoms that happen because the heart does not get blood): 8 people, 10.26%
High Blood Pressure: 7 people, 8.97%

* Approximation only. Some reports may have incomplete information.

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