Fludara and Gemzar drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Fludara (fludarabine phosphate) and Gemzar (gemcitabine hydrochloride). Common drug interactions include acute myeloid leukaemia among females and hepatic cirrhosis among males.

The phase IV clinical study analyzes what interactions people have when they take Fludara and Gemzar. It is created by eHealthMe based on reports of 43 people who take the same drugs from the FDA, and is updated regularly.

What is Fludara?

Fludara has active ingredients of fludarabine phosphate. eHealthMe is studying from 46,686 Fludara users. Check the latest studies of Fludara.

What is Gemzar?

Gemzar has active ingredients of gemcitabine hydrochloride. It is often used in pancreatic carcinoma. eHealthMe is studying from 20,315 Gemzar users. Check the latest studies of Gemzar.

On Aug, 12, 2026

43 people who take Fludara and Gemzar together, and have interactions are studied.

What are the common drug interactions of Fludara and Gemzar, by gender? *:

female:

Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
Acute leukaemia (blood cancer)
Death
Dyspnoea (difficult or laboured respiration)
Abdominal mass (localized enlargement or swelling in the human abdomen)
Abdominal pain
Aphthous ulcer (mouth ulcer)
Bacterial sepsis
Catheter site haematoma (blood clot at catheter site)
Chronic graft versus host disease (immune cells attack the host's body cells after transplant)

male:

Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
Febrile neutropenia (fever with reduced white blood cells)
Pneumonia
Pyrexia (fever)
Renal cancer (cancer of kidney)
Tonsillitis (inflammation of tonsil)
Abdominal pain
Abdominal pain upper
Anaemia (lack of blood)
Asthenia (weakness)

What are the common drug interactions of Fludara and Gemzar, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Hypochloraemia (electrolyte disturbance in which there is an abnormally low level of the chloride ion in the blood)
Inappropriate antidiuretic hormone secretion
Febrile neutropenia (fever with reduced white blood cells)
Groin infection (infection in groin)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Neoplasm progression (growth of tumour)
Tonsillitis (inflammation of tonsil)

30-39:

n/a

40-49:

n/a

50-59:

Febrile neutropenia (fever with reduced white blood cells)
Pyrexia (fever)
Abdominal mass (localized enlargement or swelling in the human abdomen)
Abdominal pain
Aphthous ulcer (mouth ulcer)
Bacterial sepsis
Catheter site haematoma (blood clot at catheter site)
Chronic graft versus host disease (immune cells attack the host's body cells after transplant)
Chronic lymphocytic leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell))
Colitis (inflammation of colon)

60+:

Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Cardiac arrest
Cardiac failure congestive
Cellulitis (infection under the skin)
Death
Disease progression
Fatigue (feeling of tiredness)
Hypotension (abnormally low blood pressure)

What are the existing conditions these people have? *

Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 14 people, 32.56%
High Blood Pressure: 12 people, 27.91%
Bronchial Carcinoma (lung cancer): 12 people, 27.91%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 12 people, 27.91%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 9 people, 20.93%
Diffuse Large B-Cell Lymphoma Recurrent (recurrent cancer of b cells, a type of white blood cell): 7 people, 16.28%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 4 people, 9.30%

* Approximation only. Some reports may have incomplete information.

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