Fludara and Motrin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Fludara (fludarabine phosphate) and Motrin (ibuprofen). Common drug interactions include acquired hypogammaglobulinaemia among females and neurotoxicity among males.

The phase IV clinical study analyzes what interactions people have when they take Fludara and Motrin. It is created by eHealthMe based on reports of 25 people who take the same drugs from the FDA, and is updated regularly.

What is Fludara?

Fludara has active ingredients of fludarabine phosphate. eHealthMe is studying from 46,686 Fludara users. Check the latest studies of Fludara.

What is Motrin?

Motrin has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 38,332 Motrin users. Check the latest studies of Motrin.

On Jul, 06, 2026

25 people who take Fludara and Motrin together, and have interactions are studied.

What are the common drug interactions of Fludara and Motrin, by gender? *:

female:

Acquired hypogammaglobulinaemia (type of primary immune deficiency disease)
Activities of daily living impaired
Adrenocortical insufficiency chronic (hormonal-disorder that occurs when the adrenal glands do not produce enough of certain hormones-chronic adrenocortical disorder)
Arthralgia (joint pain)
Autoimmune disorder (a condition in which the immune system attacks the body's normal substances and tissue)
Blood creatine phosphokinase increased
C-reactive protein increased
Cardiac arrest
Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Dyspnoea (difficult or laboured respiration)

male:

Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system)
Optic neuritis (optic nerve inflammation)
Asthenia (weakness)
Myelitis (infection or the inflammation of white matter or gray matter of spinal cord which is a part of central nervous system)
Neuropathy peripheral (surface nerve damage)
Urinary incontinence (inability to control the flow of urine and involuntary urination)
Dysphagia (a condition in which swallowing is difficult or painful)
Macular degeneration (painless eye condition that leads to the gradual loss of central vision)
Retinopathy (acute damage to the retina of the eye)
Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)

What are the common drug interactions of Fludara and Motrin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Dysphagia (a condition in which swallowing is difficult or painful)
Fatigue (feeling of tiredness)

30-39:

n/a

40-49:

n/a

50-59:

Eye haemorrhage (bleeding in the eye)
Optic atrophy (the loss of a proportion of optic disc nerve fibres)
Optic ischaemic neuropathy (optic nerve damage due to lack of blood supply)
Optic neuritis (optic nerve inflammation)
Papilloedema (optic disc swelling)
Scotoma (an area of diminished vision within the visual field)
Visual disturbance
Visual field defect
Anaemia haemolytic autoimmune (a condition in which the immune system attacks the red blood cells, resulting in fewer of these oxygen-transporting cells)
B-cell small lymphocytic lymphoma (blood cancer affecting b cells)

60+:

Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system)
Cataract (clouding of the lens inside the eye)
Urinary incontinence (inability to control the flow of urine and involuntary urination)
Macular degeneration (painless eye condition that leads to the gradual loss of central vision)
Optic neuropathy (optic nerve damage)
Retinopathy (acute damage to the retina of the eye)
Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
Blindness
Hypotension (abnormally low blood pressure)
Inflammation

What are the existing conditions these people have? *

Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 8 people, 32.00%
Diarrhea: 3 people, 12.00%
Multiple Myeloma (cancer of the plasma cells): 2 people, 8.00%
Fever: 2 people, 8.00%
Anaemia (lack of blood): 2 people, 8.00%

* Approximation only. Some reports may have incomplete information.

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