Fludarabine phosphate and Compazine drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Fludarabine phosphate (fludarabine phosphate) and Compazine (prochlorperazine maleate). Common drug interactions include neutrophil count decreased among females and febrile neutropenia among males.
The phase IV clinical study analyzes what interactions people have when they take Fludarabine phosphate and Compazine. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.
What is Fludarabine phosphate?
Fludarabine phosphate has active ingredients of fludarabine phosphate. eHealthMe is studying from 12,840 Fludarabine phosphate users. Check the latest studies of Fludarabine phosphate.
What is Compazine?
Compazine has active ingredients of prochlorperazine maleate. It is often used in indigestion. eHealthMe is studying from 13,646 Compazine users. Check the latest studies of Compazine.
18 people who take Fludarabine phosphate and Compazine together, and have interactions are studied.

What are the common drug interactions of Fludarabine Phosphate and Compazine, by gender? *:
female:
- Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
- Platelet count decreased
- White blood cell count decreased
- Cystitis (inflammation of the wall of the bladder)
- Dysuria (painful or difficult urination)
- Fatigue (feeling of tiredness)
- Haematuria (presence of blood in urine)
- Haemorrhage urinary tract (bleeding from uterine)
- Influenza
- Micturition urgency (urgency to pass the urine)
male:
- Febrile neutropenia (fever with reduced white blood cells)
- Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
- Aphasia (damage to the parts of the brain that control language)
- Arthralgia (joint pain)
- Arthritis (form of joint disorder that involves inflammation of one or more joints)
- Arthropathy
- Astigmatism (refractive error of the eye in which parallel rays of light from an external source do not converge on a single focal point on the retina)
- Back pain
- Bone disorder
- Bone loss
What are the common drug interactions of Fludarabine Phosphate and Compazine, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Abdominal pain
- Acute myeloid leukaemia recurrent (acute cancer in which the bone marrow makes abnormal myeloblast- recurrent)
- Bacterial infection
- Blood creatinine increased
- Candida endophthalmitis (fungal infection of eye)
- Chills (felling of cold)
- Drug ineffective
- Dysphagia (a condition in which swallowing is difficult or painful)
- Enterococcal infection
- Fatigue (feeling of tiredness)
30-39:
- Neoplasm progression (growth of tumour)
40-49:
n/a
50-59:
- Neuropathy peripheral (surface nerve damage)
- Nocturia (the need to get up in the night to urinate)
- Oropharyngeal pain
- Pneumonia
- Polyomavirus test positive
- Respiratory failure (inadequate gas exchange by the respiratory system)
- Rhinorrhoea (watery mucus discharge from the nose)
- Sinus congestion (blockage of sinus)
- Sinus headache (headache caused by sinus infections)
- Skin hyperpigmentation (disorders affect the colour of your skin)
60+:
- Febrile neutropenia (fever with reduced white blood cells)
- Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
- Arthropathy
- Astigmatism (refractive error of the eye in which parallel rays of light from an external source do not converge on a single focal point on the retina)
- Back pain
- Bone disorder
- Bone loss
- Bone marrow oedema (inflammation that causes much than the needed fluid in a bone)
- Bone pain
- Cardiomyopathy (weakening of the heart muscle)
What are the existing conditions these people have? *
- Nausea (feeling of having an urge to vomit): 6 people, 33.33%
- Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 5 people, 27.78%
- Diarrhea: 3 people, 16.67%
- Stress And Anxiety: 3 people, 16.67%
- Bone Marrow Conditioning Regimen: 3 people, 16.67%
- Metastatic Malignant Melanoma (spreadable cancer tumour of melanine): 2 people, 11.11%
- Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 2 people, 11.11%
- Pain: 2 people, 11.11%
- Joint Pain: 2 people, 11.11%
- Hypokalemia (low potassium): 2 people, 11.11%
* Approximation only. Some reports may have incomplete information.
Do you take Fludarabine phosphate and Compazine?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Fludarabine phosphate (12,840 reports)
- Compazine (13,646 reports)
Browse all drug interactions of Fludarabine phosphate and Compazine:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Fludarabine phosphate:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Compazine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Fludarabine phosphate and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Compazine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on fludarabine phosphate and prochlorperazine maleate (the active ingredients of Fludarabine phosphate and Compazine, respectively), and Fludarabine phosphate and Compazine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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