Fluoride and Sirolimus drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Fluoride (fluoride) and Sirolimus (sirolimus). Common drug interactions include cough among females and fall among males.

The phase IV clinical study analyzes what interactions people have when they take Fluoride and Sirolimus. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Fluoride?

Fluoride has active ingredients of fluoride. eHealthMe is studying from 2,301 Fluoride users. Check the latest studies of Fluoride.

What is Sirolimus?

Sirolimus has active ingredients of sirolimus. eHealthMe is studying from 11,823 Sirolimus users. Check the latest studies of Sirolimus.

On Jul, 11, 2026

15 people who take Fluoride and Sirolimus together, and have interactions are studied.

Fluoride and Sirolimus drug interactions.

What are the common drug interactions of Fluoride and Sirolimus, by gender? *:

female:

Cough
Embolic stroke (stroke due to obstruction due to an embolus)
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Respiratory failure (inadequate gas exchange by the respiratory system)
Restrictive cardiomyopathy (a condition in which the walls of the lower chambers of the heart (the ventricles) are abnormally rigid and lack the flexibility)
Sepsis (a severe blood infection that can lead to organ failure and death)
Alanine aminotransferase increased
Aspartate aminotransferase increased
Blood bilirubin increased
Depression

male:

Fall
Hip fracture
Neuropathy peripheral (surface nerve damage)
Acute graft versus host disease (acute complication following an allogeneic tissue/blood transplant)
Fluid retention (an abnormal accumulation of fluid in the blood)
Peripheral swelling
Rash
Urticaria (rash of round, red welts on the skin that itch intensely)
Weight increased

What are the common drug interactions of Fluoride and Sirolimus, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Alanine aminotransferase increased
Anaemia (lack of blood)
Aspartate aminotransferase increased
Blood bilirubin increased
Cough
Diarrhoea
Febrile neutropenia (fever with reduced white blood cells)
Gamma-glutamyltransferase increased
Hyperglycaemia (high blood sugar)
Hyperkalaemia (damage to or disease of the kidney)

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Neuropathy peripheral (surface nerve damage)
Anaemia (lack of blood)
Cough
Depression
Fatigue (feeling of tiredness)
Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
Hypophagia (reduced food intake)
Idiopathic pneumonia syndrome (pneumonia-like symptoms)
Night sweats (sweating in night)
Post transplant lymphoproliferative disorder

60+:

Embolic stroke (stroke due to obstruction due to an embolus)
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Respiratory failure (inadequate gas exchange by the respiratory system)
Restrictive cardiomyopathy (a condition in which the walls of the lower chambers of the heart (the ventricles) are abnormally rigid and lack the flexibility)
Sepsis (a severe blood infection that can lead to organ failure and death)
Acute graft versus host disease (acute complication following an allogeneic tissue/blood transplant)
Hepatorenal failure (decrease in kidney function in a person with a severe liver disorder)
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)

What are the existing conditions these people have? *

Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 8 people, 53.33%
Pain: 8 people, 53.33%
Stress And Anxiety: 7 people, 46.67%
High Blood Pressure: 6 people, 40.00%
Insomnia (sleeplessness): 6 people, 40.00%
Diabetes: 6 people, 40.00%
Hepatitis B: 4 people, 26.67%
High Blood Cholesterol: 4 people, 26.67%
Mood Swings (an extreme or rapid change in mood): 4 people, 26.67%
Blood Pressure Abnormal: 4 people, 26.67%

* Approximation only. Some reports may have incomplete information.

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