Fluorouracil and Erythromycin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Fluorouracil (fluorouracil) and Erythromycin (erythromycin). Common drug interactions include infusion site bruising among females and functional gastrointestinal disorder among males.

The phase IV clinical study analyzes what interactions people have when they take Fluorouracil and Erythromycin. It is created by eHealthMe based on reports of 38 people who take the same drugs from the FDA, and is updated regularly.

What is Fluorouracil?

Fluorouracil has active ingredients of fluorouracil. It is often used in colon cancer metastatic. eHealthMe is studying from 97,087 Fluorouracil users. Check the latest studies of Fluorouracil.

What is Erythromycin?

Erythromycin has active ingredients of erythromycin. It is often used in acne. eHealthMe is studying from 12,563 Erythromycin users. Check the latest studies of Erythromycin.

On Jul, 20, 2026

38 people who take Fluorouracil and Erythromycin together, and have interactions are studied.

Fluorouracil and Erythromycin drug interactions.

What are the common drug interactions of Fluorouracil and Erythromycin, by gender? *:

female:

Infusion site bruising
Inner ear disorder
Loss of consciousness
Oral lichen planus (a chronic inflammatory disease that causes bilateral white striations, papules, or plaques on the buccal mucosa)
Periodic limb movement disorder
Pneumonia
Post procedural complication
Post procedural infection
Renal failure (kidney dysfunction)
Restless legs syndrome (a powerful urge to move your legs)

male:

Functional gastrointestinal disorder (functional problem in separate organs of gastrointestinal system)
Diarrhoea
Abnormal faeces (abnormal stool)
Asthma
Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
Bladder cancer
Blood creatinine increased
Blood fibrinogen increased
Blood lactate dehydrogenase increased
Bone density decreased

What are the common drug interactions of Fluorouracil and Erythromycin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Diarrhoea
Nausea (feeling of having an urge to vomit)
Vomiting
Abdominal pain
Fatigue (feeling of tiredness)
Hypocalcaemia (levels of calcium in blood serum are abnormally low)
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
Neutropenia (an abnormally low number of neutrophils)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Pyrexia (fever)

50-59:

Functional gastrointestinal disorder (functional problem in separate organs of gastrointestinal system)
Hypertension (high blood pressure)
Chills (felling of cold)
Bone density decreased
Chronic kidney disease
Emotional distress
Exercise tolerance decreased
Foot fracture
Lumbar vertebral fracture
Mobility decreased (ability to move is reduced)

60+:

Pyrexia (fever)
Abdominal distension
Injection site mass
Malaise (a feeling of general discomfort or uneasiness)
Muscle strain (an injury to a muscle in which the muscle fibres tear)
Pain
Rash erythematous (redness of the skin)
Rash pruritic (redness with itching)
Scar
Tremor (trembling or shaking movements in one or more parts of your body)

What are the existing conditions these people have? *

Skin Cancer: 5 people, 13.16%
Primary Immunodeficiency Syndrome: 5 people, 13.16%
Infection: 5 people, 13.16%
Squamous Cell Carcinoma (a cancer of a kind of epithelial cell): 3 people, 7.89%
Colon Cancer: 3 people, 7.89%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 5.26%
High Blood Pressure: 2 people, 5.26%
Drowsiness: 2 people, 5.26%
Diabetes: 2 people, 5.26%
Colorectal Cancer Metastatic (cancer of colon and rectal spreads to other parts): 2 people, 5.26%

* Approximation only. Some reports may have incomplete information.

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