Fluphenazine decanoate and Diphen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Fluphenazine decanoate (fluphenazine decanoate) and Diphen (diphenhydramine hydrochloride). Common drug interactions include thought insertion among females and electrocardiogram qt prolonged among males.

The phase IV clinical study analyzes what interactions people have when they take Fluphenazine decanoate and Diphen. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Fluphenazine decanoate?

Fluphenazine decanoate has active ingredients of fluphenazine decanoate. eHealthMe is studying from 599 Fluphenazine decanoate users. Check the latest studies of Fluphenazine decanoate.

What is Diphen?

Diphen has active ingredients of diphenhydramine hydrochloride. It is often used in insomnia. eHealthMe is studying from 115,432 Diphen users. Check the latest studies of Diphen.

On Jul, 14, 2026

12 people who take Fluphenazine decanoate and Diphen together, and have interactions are studied.

Fluphenazine decanoate and Diphen drug interactions.

What are the common drug interactions of Fluphenazine Decanoate and Diphen, by gender? *:

female:

Thought insertion (the idea that another thinks through the mind of the person)
Transient psychosis (short term loss of contact with reality)
Tremor (trembling or shaking movements in one or more parts of your body)
Type 2 diabetes mellitus
Urinary incontinence (inability to control the flow of urine and involuntary urination)
Vulvovaginal injury
Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)
Psychotic disorder
Agitation (state of anxiety or nervous excitement)
Pyrexia (fever)

male:

Electrocardiogram qt prolonged
Blood prolactin increased
Delirium (wild excitement)
Drug abuse
Fatigue (feeling of tiredness)
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Schizophreniform disorder (mental disorder is diagnosed when the symptom criteria for schizophrenia are met, but the duration is too short and social and occupational functioning)
Sepsis (a severe blood infection that can lead to organ failure and death)
Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)
Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)

What are the common drug interactions of Fluphenazine Decanoate and Diphen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Anxiety
Bradykinesia (decreased bodily movement. it is associated with basal ganglia diseases)
Coprolalia (uncontrolled, often obsessive use of obscene or scatological language)
Decreased appetite
Dyskinesia (abnormality or impairment of voluntary movement)
Loss of consciousness
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Somnambulism (sleep walking)
Somnolence (a state of near-sleep, a strong desire for sleep)
Tic (a sudden, repetitive, nonrhythmic motor movement or vocalization involving discrete muscle groups)

20-29:

n/a

30-39:

Drug abuse
Drug dependence
Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)
Abasia (inability to walk)
Agitation (state of anxiety or nervous excitement)
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Drug level increased
Extrapyramidal disorder (involuntary muscle spasms in the face and neck)
Faecal incontinence (a lack of control over passing stool)
Hallucination, auditory (perceiving sounds without auditory stimulus)

40-49:

Aggression
Agitation (state of anxiety or nervous excitement)
Arrhythmia (irregular heartbeat)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Cardiac arrest
Cough
Drug ineffective
Electrocardiogram qt prolonged
Hypotension (abnormally low blood pressure)
Loss of consciousness

50-59:

n/a

60+:

Fatigue (feeling of tiredness)
Torsade de pointes (a abnormal heart rate with abnormal beating pattern)
Anger
Antisocial behaviour
Bipolar i disorder (mood disorder that is characterized by at least one manic or mixed episode)
Breast cancer
Chest pain
Constipation
Cyclothymic disorder (mood disorder)
Delusion (a false belief or opinion)

What are the existing conditions these people have? *

Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 3 people, 25.00%
Tic (a sudden, repetitive, nonrhythmic motor movement or vocalization involving discrete muscle groups): 2 people, 16.67%
Stress And Anxiety: 2 people, 16.67%
Gilles De La Tourette Syndrome (a condition that causes people to make repeated, quick movements or sounds that they cannot control): 2 people, 16.67%
Weight Increased: 1 person, 8.33%
Urinary Tract Infection: 1 person, 8.33%
Schizoaffective Disorder Bipolar Type (mental illness featuring schizophrenia and a mood disorder with mania): 1 person, 8.33%
Schizoaffective Disorder (a mental disorder characterized by disordered thought): 1 person, 8.33%
Ischaemic Cardiomyopathy (weakness in the muscle of the heart due to inadequate oxygen delivery to the myocardium with coronary artery disease): 1 person, 8.33%
Generalized Anxiety Disorder (excessive, uncontrollable, unexplained and often irrational worry): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

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