Flurbiprofen and Fentanyl citrate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Flurbiprofen (flurbiprofen) and Fentanyl citrate (fentanyl citrate). Common drug interactions include electrocardiogram st segment depression among females and drug rash with eosinophilia and systemic symptoms among males.

The phase IV clinical study analyzes what interactions people have when they take Flurbiprofen and Fentanyl citrate. It is created by eHealthMe based on reports of 73 people who take the same drugs from the FDA, and is updated regularly.

What is Flurbiprofen?

Flurbiprofen has active ingredients of flurbiprofen. It is often used in rheumatoid arthritis. eHealthMe is studying from 2,677 Flurbiprofen users. Check the latest studies of Flurbiprofen.

What is Fentanyl citrate?

Fentanyl citrate has active ingredients of fentanyl citrate. It is often used in pain. eHealthMe is studying from 21,294 Fentanyl citrate users. Check the latest studies of Fentanyl citrate.

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On Jul, 04, 2026

73 people who take Flurbiprofen and Fentanyl citrate together, and have interactions are studied.

Flurbiprofen and Fentanyl citrate drug interactions.

What are the common drug interactions of Flurbiprofen and Fentanyl Citrate, by gender? *:

female:

Electrocardiogram st segment depression
Febrile neutropenia (fever with reduced white blood cells)
Oxygen saturation decreased
Vocal cord paralysis
Wheezing (a high-pitched whistling sound made while you breath)
Alanine aminotransferase increased
Altered state of consciousness (altered state of mind)
Anaesthetic complication
Ascites (accumulation of fluid in the abdominal cavity)
Aspartate aminotransferase increased

male:

Drug rash with eosinophilia and systemic symptoms (adverse drug reactions with rash)
Renal impairment (severely reduced kidney function)
Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs)
Biliary tract infection
Febrile neutropenia (fever with reduced white blood cells)
Hyperthermia malignant (disease passed down through families that causes a fast rise in body temperature (fever) and severe muscle contractions)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood)
Pneumonia
Polyarthritis (arthritis which involves 5 or more joints simultaneously)

What are the common drug interactions of Flurbiprofen and Fentanyl Citrate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Cerebral haemorrhage (bleeding within the brain)
Haemolytic uraemic syndrome (blood clotting disease caused by e. coli infection, birth control pills, pneumonia, medications, and more)
Infection
Blood osmolarity increased
Enterococcal infection
Enterococcal sepsis
Neuroblastoma (a cancer that forms in your nerve tissue)

10-19:

Drug rash with eosinophilia and systemic symptoms (adverse drug reactions with rash)
Adenovirus infection
Cytomegalovirus test positive
Diarrhoea
Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
Hyperglycaemia (high blood sugar)
Ileus paralytic (obstruction of the intestine due to paralysis of the intestinal muscles)
Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
Respiratory disorder (respiratory disease)
Thrombotic microangiopathy (a pathology that results in thrombosis in capillaries and arterioles, due to an endothelial injury)

20-29:

Atlantoaxial instability (instability of the union between the first and second cervical vertebrae)
Blood pressure increased
Hyperuricaemia (level of uric acid in the blood that is abnormally high)
Post procedural haemorrhage (post procedural bleeding)
Road traffic accident
Weight increased

30-39:

Hypercapnia (too much smoke)
Laryngospasm (an uncontrolled/involuntary muscular contraction of larynx)
Obstructive airways disorder (a progressive disease that makes it hard to breathe)
Respiratory arrest (cessation of normal respiration due to failure of the lungs to function effectively)
Respiratory depression (respiration has a rate below 12 breaths)
Hepatic function abnormal

40-49:

Hydrocephalus (water on the brain)
Placenta praevia (a condition that occurs during pregnancy when the placenta is abnormally placed, and partially or totally covers the cervix)
Premature baby
Threatened labour (premature labour is the onset of labour between 24 and 37 weeks of pregnancy)
Neuromuscular block prolonged
Anaesthetic complication
Drug exposure during pregnancy
Haemorrhagic cerebral infarction (brain stroke with bleeding)

50-59:

Venoocclusive liver disease (small veins in the liver are obstructed)
Constipation
Oesophageal carcinoma (cancer tumour of oesophagus)
Alanine aminotransferase increased
Altered state of consciousness (altered state of mind)
Aspartate aminotransferase increased
Blood creatine phosphokinase increased
Cardiac disorder
Chills (felling of cold)
Death

60+:

Ileus (a painful obstruction of the ileum or other part of the intestine)
Renal impairment (severely reduced kidney function)
Upper airway obstruction
Cancer pain
Decreased appetite
Drug eruption (adverse drug reaction of the skin)
Pneumonia
Drug ineffective
Febrile neutropenia (fever with reduced white blood cells)
Lung infection

What are the existing conditions these people have? *

Fever: 16 people, 21.92%
Constipation: 15 people, 20.55%
Infection: 11 people, 15.07%
Nausea (feeling of having an urge to vomit): 9 people, 12.33%
Cancer Pain: 8 people, 10.96%
Insomnia (sleeplessness): 7 people, 9.59%
Bone Marrow Conditioning Regimen: 7 people, 9.59%
Rectal Cancer (cancer of rectum): 5 people, 6.85%
Anaesthesia: 5 people, 6.85%
Rashes (redness): 4 people, 5.48%

* Approximation only. Some reports may have incomplete information.

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