Focalin and Benzonatate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Focalin (dexmethylphenidate hydrochloride) and Benzonatate (benzonatate). Common drug interactions include arthralgia among females and anaphylactic reaction among males.

The phase IV clinical study analyzes what interactions people have when they take Focalin and Benzonatate. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Focalin?

Focalin has active ingredients of dexmethylphenidate hydrochloride. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 4,781 Focalin users. Check the latest studies of Focalin.

What is Benzonatate?

Benzonatate has active ingredients of benzonatate. It is often used in cough. eHealthMe is studying from 17,274 Benzonatate users. Check the latest studies of Benzonatate.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

12 people who take Focalin and Benzonatate together, and have interactions are studied.

Focalin and Benzonatate drug interactions.

What are the common drug interactions of Focalin and Benzonatate, by gender? *:

female:

Arthralgia (joint pain)
Back pain
Confusional state
Therapeutic response unexpected
Fall
Gastritis (inflammation of stomach)
Glycosylated haemoglobin decreased
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Impaired gastric emptying
Lower limb fracture

male:

Anaphylactic reaction (serious allergic reaction)
Asthenia (weakness)
Bronchial hyperreactivity
Nephrolithiasis (calculi in the kidneys)
Therapeutic response unexpected
Calculus urinary (stone in urinary system)
Migraine (headache)
Presyncope

What are the common drug interactions of Focalin and Benzonatate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Papillary thyroid cancer

50-59:

n/a

60+:

Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Arthralgia (joint pain)
Back pain
Confusional state
Therapeutic response unexpected
Weight decreased

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 11 people, 91.67%
Nausea (feeling of having an urge to vomit): 4 people, 33.33%
Migraine (headache): 4 people, 33.33%
Gallstones (stone formation by bile component): 4 people, 33.33%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 4 people, 33.33%
Blood Testosterone Decreased: 4 people, 33.33%
Type 2 Diabetes: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

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