Focalin and Oxycodone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Focalin (dexmethylphenidate hydrochloride) and Oxycodone (oxycodone hydrochloride). Common drug interactions include chronic kidney disease among females and dermatitis among males.

The phase IV clinical study analyzes what interactions people have when they take Focalin and Oxycodone. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Focalin?

Focalin has active ingredients of dexmethylphenidate hydrochloride. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 4,781 Focalin users. Check the latest studies of Focalin.

What is Oxycodone?

Oxycodone has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 162,592 Oxycodone users. Check the latest studies of Oxycodone.

On Jul, 13, 2026

19 people who take Focalin and Oxycodone together, and have interactions are studied.

Focalin and Oxycodone drug interactions.

What are the common drug interactions of Focalin and Oxycodone, by gender? *:

female:

Chronic kidney disease
Drug ineffective
Diarrhoea
Feeling jittery
Malaise (a feeling of general discomfort or uneasiness)
Alopecia (absence of hair from areas of the body)
Blood calcium increased
Chest pain
Decreased appetite
Drug tolerance decreased

male:

Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Stomatitis (inflammation of mucous membrane of mouth)
Hypoaesthesia (reduced sense of touch or sensation)
Influenza
Myalgia (muscle pain)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Renal failure (kidney dysfunction)
Respiratory disorder (respiratory disease)
Road traffic accident
Vitamin d deficiency

What are the common drug interactions of Focalin and Oxycodone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Ear disorder
Malaise (a feeling of general discomfort or uneasiness)

20-29:

Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Stomatitis (inflammation of mucous membrane of mouth)
Dermatitis atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder)
Eye infection
Memory impairment
Nervousness
Somnolence (a state of near-sleep, a strong desire for sleep)

30-39:

n/a

40-49:

Head injury
Headache (pain in head)
Road traffic accident

50-59:

Dry mouth
Dysgeusia (disorder of the sense of taste)
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Haemoglobin decreased
Headache (pain in head)
Hypoaesthesia (reduced sense of touch or sensation)
Influenza
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Myalgia (muscle pain)

60+:

Chronic kidney disease
Renal failure (kidney dysfunction)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 21.05%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 21.05%
Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 3 people, 15.79%
Asthma: 2 people, 10.53%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 10.53%
Gastric Ulcer (stomach ulcer): 2 people, 10.53%
Sleep Disorder: 1 person, 5.26%
Hepatitis C: 1 person, 5.26%
Arthropathy: 1 person, 5.26%
Joint Pain: 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

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