Focalin and Pepcid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Focalin (dexmethylphenidate hydrochloride) and Pepcid (famotidine). Common drug interactions include abdominal pain among females.

The phase IV clinical study analyzes what interactions people have when they take Focalin and Pepcid. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Focalin?

Focalin has active ingredients of dexmethylphenidate hydrochloride. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 4,781 Focalin users. Check the latest studies of Focalin.

What is Pepcid?

Pepcid has active ingredients of famotidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 55,774 Pepcid users. Check the latest studies of Pepcid.

On Jul, 17, 2026

20 people who take Focalin and Pepcid together, and have interactions are studied.

What are the common drug interactions of Focalin and Pepcid, by gender? *:

female:

Abdominal pain
Constipation
Bacterial infection
Blood pressure increased
Cough
Disability
Dry mouth
Fall
Gastric disorder (disease of stomach)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)

male:

n/a

What are the common drug interactions of Focalin and Pepcid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Constipation
Bacterial infection
Cough
Upper respiratory tract infection

20-29:

Migraine (headache)
Abortion spontaneous (naturally occurring miscarriage)

30-39:

n/a

40-49:

Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Papillary thyroid cancer

50-59:

Abdominal pain
Dental discomfort
Depression
Gallbladder disorder
Malaise (a feeling of general discomfort or uneasiness)
Gastric disorder (disease of stomach)
Nasopharyngitis (inflammation of the nasopharynx)

60+:

n/a

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 6 people, 30.00%
Migraine (headache): 4 people, 20.00%
Cystic Fibrosis (disease of the secretary glands): 4 people, 20.00%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 4 people, 20.00%
Drowsiness: 3 people, 15.00%
Type 2 Diabetes: 1 person, 5.00%
Psoriasis (immune-mediated disease that affects the skin): 1 person, 5.00%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 5.00%
Food Allergy: 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

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