Focalin and Vimpat drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Focalin (dexmethylphenidate hydrochloride) and Vimpat (lacosamide). Common drug interactions include blood pressure decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Focalin and Vimpat. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Focalin?

Focalin has active ingredients of dexmethylphenidate hydrochloride. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 4,781 Focalin users. Check the latest studies of Focalin.

What is Vimpat?

Vimpat has active ingredients of lacosamide. It is often used in epilepsy. eHealthMe is studying from 20,831 Vimpat users. Check the latest studies of Vimpat.



On Jul, 31, 2026

12 people who take Focalin and Vimpat together, and have interactions are studied.

Focalin and Vimpat drug interactions.

What are the common drug interactions of Focalin and Vimpat, by gender? *:

female:

n/a

male:

  1. Blood pressure decreased
  2. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  3. Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
  4. Pyrexia (fever)
  5. Atonic seizures (minor type of seizure)
  6. Stomatitis (inflammation of mucous membrane of mouth)
  7. Cerebral disorder (brain disease)
  8. Aggression
  9. Angiofibroma (small, reddish brown or even flesh-coloured, smooth, shiny, 0.1- to 0.3 cm papules present over the sides of the nose and the medial portions of the cheeks)
  10. Chronic kidney disease

What are the common drug interactions of Focalin and Vimpat, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Fall
  2. Foaming at mouth (excess saliva secretion)
  3. Gait disturbance
  4. Herpangina (mouth blisters)
  5. Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
  6. Pyrexia (fever)
  7. Atonic seizures (minor type of seizure)
  8. Stomatitis (inflammation of mucous membrane of mouth)
  9. Aggression
  10. Angiofibroma (small, reddish brown or even flesh-coloured, smooth, shiny, 0.1- to 0.3 cm papules present over the sides of the nose and the medial portions of the cheeks)

20-29:

  1. Muscular weakness (muscle weakness)

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

  1. Chronic kidney disease
  2. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  3. Renal failure (kidney dysfunction)

What are the existing conditions these people have? *

  1. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 5 people, 41.67%
  2. Tuberous Sclerosis (a rare genetic disease that causes benign tumours to grow in the brain and other organs): 4 people, 33.33%
  3. Astrocytoma (tumour of the brain that originate in a particular kind of glial-cells): 4 people, 33.33%
  4. Sleep Disorder: 2 people, 16.67%
  5. Pain: 1 person, 8.33%
  6. Neuropathy Peripheral (surface nerve damage): 1 person, 8.33%
  7. Neuralgia (pain in one or more nerves): 1 person, 8.33%
  8. Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 1 person, 8.33%
  9. Multiple Allergies (allergy to multiple agents): 1 person, 8.33%
  10. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Focalin and Vimpat?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Focalin and Vimpat:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Focalin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Vimpat:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Focalin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Vimpat and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on dexmethylphenidate hydrochloride and lacosamide (the active ingredients of Focalin and Vimpat, respectively), and Focalin and Vimpat (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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