Folate and Colecalciferol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Folate (folic acid) and Colecalciferol (cholecalciferol). Common drug interactions include functional gastrointestinal disorder among females and anal ulcer among males.

The phase IV clinical study analyzes what interactions people have when they take Folate and Colecalciferol. It is created by eHealthMe based on reports of 70 people who take the same drugs from the FDA, and is updated regularly.

What is Folate?

Folate has active ingredients of folic acid. It is often used in rheumatoid arthritis. eHealthMe is studying from 6,546 Folate users. Check the latest studies of Folate.

What is Colecalciferol?

Colecalciferol has active ingredients of cholecalciferol. eHealthMe is studying from 21,262 Colecalciferol users. Check the latest studies of Colecalciferol.

On Jul, 07, 2026

70 people who take Folate and Colecalciferol together, and have interactions are studied.

Folate and Colecalciferol drug interactions.

What are the common drug interactions of Folate and Colecalciferol, by gender? *:

female:

Functional gastrointestinal disorder (functional problem in separate organs of gastrointestinal system)
Gait disturbance
Gout (uric acid crystals building up in the body)
Haematochezia (passage of stools containing blood)
Haemoglobin decreased
Heart rate decreased
Hepatocellular injury (liver injury)
Hospitalisation
Hypoaesthesia (reduced sense of touch or sensation)
Hypokalaemia (low potassium)

male:

Anal ulcer
Hypotension (abnormally low blood pressure)
Dyspnoea (difficult or laboured respiration)
Dyspnoea exertional (breathlessness or shortness of breath)
Eosinophilia (eosinophil count in the peripheral blood exceeds)
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Haemoglobin decreased
Headache (pain in head)
Hyperthyroidism (over activity of the thyroid gland)
Insomnia (sleeplessness)

What are the common drug interactions of Folate and Colecalciferol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Diarrhoea

20-29:

n/a

30-39:

Abdominal pain
Anaemia (lack of blood)
Asthma
Chest discomfort
Colitis (inflammation of colon)
Cough
Decreased appetite
Dyspnoea (difficult or laboured respiration)
Dyspnoea exertional (breathlessness or shortness of breath)
Eosinophilia (eosinophil count in the peripheral blood exceeds)

40-49:

Weight increased
Food allergy
Hypertension (high blood pressure)
Thyroid disorder (thyroid diseases)
Arthralgia (joint pain)
Dyspnoea (difficult or laboured respiration)
Flushing (the warm, red condition of human skin)
Influenza
Infusion related reaction
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)

50-59:

Migraine (headache)
Neuropathy peripheral (surface nerve damage)
Vision blurred
Blood pressure fluctuation
Hypotension (abnormally low blood pressure)
Dizziness
Drug ineffective
Heart rate decreased

60+:

Limb discomfort (discomfort in leg)
Anal ulcer
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Blood pressure decreased
Central nervous system lesion (an abnormality in tissue of brain or spinal cord)
Death
Hip arthroplasty
Memory impairment
Micturition disorder (disease of passing urine)
Nausea (feeling of having an urge to vomit)

What are the existing conditions these people have? *

Pain: 13 people, 18.57%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 12 people, 17.14%
High Blood Cholesterol: 10 people, 14.29%
High Blood Pressure: 10 people, 14.29%
Sleep Disorder: 9 people, 12.86%
Insomnia (sleeplessness): 7 people, 10.00%
Malignant Melanoma (skin cancer rises from melancytes): 6 people, 8.57%
Psoriasis (immune-mediated disease that affects the skin): 6 people, 8.57%
Migraine (headache): 6 people, 8.57%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 5 people, 7.14%

* Approximation only. Some reports may have incomplete information.

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