Folate and Glyburide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Folate (folic acid) and Glyburide (glyburide). Common drug interactions include non-cardiac chest pain among females and anhedonia among males.

The phase IV clinical study analyzes what interactions people have when they take Folate and Glyburide. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Folate?

Folate has active ingredients of folic acid. It is often used in rheumatoid arthritis. eHealthMe is studying from 6,546 Folate users. Check the latest studies of Folate.

What is Glyburide?

Glyburide has active ingredients of glyburide. It is often used in diabetes. eHealthMe is studying from 38,448 Glyburide users. Check the latest studies of Glyburide.



On Jul, 12, 2026

15 people who take Folate and Glyburide together, and have interactions are studied.

Folate and Glyburide drug interactions.

What are the common drug interactions of Folate and Glyburide, by gender? *:

female:

  1. Non-cardiac chest pain
  2. Obesity (having too much body fat)
  3. Occult blood positive
  4. Oesophageal disorder (disease of oesophagus)
  5. Oesophageal spasm (contraction of oesophagus)
  6. Osteoarthritis (a joint disease caused by cartilage loss in a joint)
  7. Osteoporosis (bones weak and more likely to break)
  8. Pelvic pain
  9. Pericardial effusion (fluid around the heart)
  10. Hypertension (high blood pressure)

male:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Stress
  4. Abdominal pain upper
  5. Haematochezia (passage of stools containing blood)
  6. Hypoxia (low oxygen in tissues)
  7. Pneumonia
  8. Respiratory tract infection
  9. Emotional distress
  10. Fear

What are the common drug interactions of Folate and Glyburide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
  2. Completed suicide (act of taking one's own life)
  3. Death
  4. Hypoxia (low oxygen in tissues)
  5. Pleural effusion (water on the lungs)
  6. Pneumonia bacterial (pneumonia associated with bacterial infection)
  7. Pyrexia (fever)
  8. Respiratory distress (difficulty in breathing)

20-29:

n/a

30-39:

n/a

40-49:

  1. Pain
  2. Renal disorder (kidney disease)
  3. Renal failure (kidney dysfunction)
  4. Renal impairment (severely reduced kidney function)
  5. Renal injury (kidney injury)
  6. Stress
  7. Compression fracture (fracture due to pressure caused by injury)
  8. Cough
  9. Headache (pain in head)
  10. Hypertension (high blood pressure)

50-59:

  1. Abdominal pain upper
  2. Blood cholesterol increased
  3. Carotid artery stenosis (narrowing of carotid artery)
  4. Dyspnoea (difficult or laboured respiration)
  5. Gastric ulcer haemorrhage (bleeding ulcer of stomach)
  6. Haematochezia (passage of stools containing blood)
  7. Haematoma (collection of blood outside the blood vessels)
  8. Haemoglobin decreased
  9. Hypertension (high blood pressure)
  10. Hypoaesthesia (reduced sense of touch or sensation)

60+:

  1. Asthenia (weakness)
  2. Back pain
  3. Arthralgia (joint pain)
  4. Blood albumin decreased
  5. Blood glucose increased
  6. Blood sodium decreased
  7. Blood urea increased
  8. Bone marrow disorder
  9. Bone pain
  10. Cardiovascular disorder (heart diseases)

What are the existing conditions these people have? *

  1. Type 2 Diabetes: 2 people, 13.33%
  2. Bone Marrow Conditioning Regimen: 2 people, 13.33%
  3. Pain: 2 people, 13.33%
  4. Nicotine Dependence: 2 people, 13.33%
  5. Nausea (feeling of having an urge to vomit): 2 people, 13.33%
  6. Stress And Anxiety: 2 people, 13.33%
  7. Hepatitis C: 1 person, 6.67%
  8. Back Pain: 1 person, 6.67%
  9. Bipolar I Disorder (mood disorder that is characterized by at least one manic or mixed episode): 1 person, 6.67%
  10. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Folate and Glyburide?

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- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Folate and Glyburide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Folate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Glyburide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Folate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Glyburide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on folic acid and glyburide (the active ingredients of Folate and Glyburide, respectively), and Folate and Glyburide (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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