Folate and Prograf drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Folate (folic acid) and Prograf (tacrolimus). Common drug interactions include gastrointestinal haemorrhage among females and renal failure among males.

The phase IV clinical study analyzes what interactions people have when they take Folate and Prograf. It is created by eHealthMe based on reports of 36 people who take the same drugs from the FDA, and is updated regularly.

What is Folate?

Folate has active ingredients of folic acid. It is often used in rheumatoid arthritis. eHealthMe is studying from 6,546 Folate users. Check the latest studies of Folate.

What is Prograf?

Prograf has active ingredients of tacrolimus. It is often used in kidney transplant. eHealthMe is studying from 42,230 Prograf users. Check the latest studies of Prograf.

On Jul, 08, 2026

36 people who take Folate and Prograf together, and have interactions are studied.

What are the common drug interactions of Folate and Prograf, by gender? *:

female:

Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Haemodialysis complication
Haemorrhage (bleeding)
Lip swelling
Loss of consciousness
Nervous system disorder (a general class of medical conditions affecting the nervous system)
Pneumonia
Renal failure acute (rapid kidney dysfunction)
Road traffic accident
Transplant rejection (a transplant material is not worked)

male:

Renal failure (kidney dysfunction)
Bacteraemia (presence of bacteria in the blood)
Blood bilirubin increased
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Bronchopulmonary aspergillosis (lung disorder caused by aspergillus fungi)
Burkholderia cepacia complex infection (complex infection by group of bacteria burkholderia cepacia -resistant to common antibiotics)
Cholecystitis (infection of gallbladder)
Cytomegalovirus infection
Demyelination (loss of the myelin covering of some nerve fibres resulting in their impaired function)
Dyspepsia (indigestion)

What are the common drug interactions of Folate and Prograf, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Cardiac tamponade (fluid accumulates in heart covering)

30-39:

Abdominal pain
Bacteraemia (presence of bacteria in the blood)
Burkholderia cepacia complex infection (complex infection by group of bacteria burkholderia cepacia -resistant to common antibiotics)
Cholecystitis (infection of gallbladder)
Death
Dyspnoea (difficult or laboured respiration)
Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
Liver injury
Nausea (feeling of having an urge to vomit)
Pancreatitis (inflammation of pancreas)

40-49:

Renal failure (kidney dysfunction)
Chronic kidney disease
Drug toxicity
Hypertension (high blood pressure)
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Neck pain
Nephrogenic anaemia (anaemia due to kidney disease)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Air embolism
Alcohol withdrawal syndrome

50-59:

Appendicitis (inflammation of the appendix)
Bacterial infection

60+:

Accident
Concussion (short loss of normal brain function in response to a head injury)
Anaemia (lack of blood)
Bacteraemia (presence of bacteria in the blood)
Bk virus infection
Blood bilirubin increased
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cytomegalovirus infection
Demyelination (loss of the myelin covering of some nerve fibres resulting in their impaired function)
Drug ineffective

What are the existing conditions these people have? *

Depression: 11 people, 30.56%
High Blood Cholesterol: 9 people, 25.00%
Cardiac Disorder: 6 people, 16.67%
Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 6 people, 16.67%
Swelling: 6 people, 16.67%
Immune System Disorder: 5 people, 13.89%
Blood Glucose Abnormal: 5 people, 13.89%
Stress And Anxiety: 5 people, 13.89%
Blood Pressure Abnormal: 5 people, 13.89%
Hypersensitivity: 5 people, 13.89%

* Approximation only. Some reports may have incomplete information.

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