Formoterol fumarate and Combivent drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Formoterol fumarate (formoterol fumarate) and Combivent (albuterol sulfate; ipratropium bromide). Common drug interactions include diastolic dysfunction among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Formoterol fumarate and Combivent. It is created by eHealthMe based on reports of 74 people who take the same drugs from the FDA, and is updated regularly.

What is Formoterol fumarate?

Formoterol fumarate has active ingredients of formoterol fumarate. eHealthMe is studying from 4,968 Formoterol fumarate users. Check the latest studies of Formoterol fumarate.

What is Combivent?

Combivent has active ingredients of albuterol sulfate; ipratropium bromide. It is often used in asthma. eHealthMe is studying from 35,341 Combivent users. Check the latest studies of Combivent.



On Jul, 31, 2026

74 people who take Formoterol fumarate and Combivent together, and have interactions are studied.

Formoterol fumarate and Combivent drug interactions.

What are the common drug interactions of Formoterol Fumarate and Combivent, by gender? *:

female:

  1. Diastolic dysfunction
  2. Disease recurrence
  3. Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
  4. Dyspnoea exertional (breathlessness or shortness of breath)
  5. Embolism venous (embolus may pass into the arterial system)
  6. Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs)
  7. Female genital tract fistula (passage in genital tract of female)
  8. Fungal infection
  9. Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
  10. Iron deficiency anaemia

male:

  1. Pneumonia
  2. Acute respiratory failure
  3. Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs)
  4. Fatigue (feeling of tiredness)
  5. Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
  6. Increased upper airway secretion
  7. Influenza
  8. Palpitations (feelings or sensations that your heart is pounding or racing)
  9. Tachycardia (a heart rate that exceeds the range of 100 beats/min)
  10. Weight decreased

What are the common drug interactions of Formoterol Fumarate and Combivent, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  2. Bronchitis bacterial (inflammation of the mucous membrane in the bronchial tubes due to bacterial infection)
  3. Cellulitis (infection under the skin)
  4. Drug dependence
  5. Eosinophil count decreased
  6. Escherichia test positive
  7. Heart rate increased
  8. Hypersensitivity
  9. Lung neoplasm malignant (cancer tumour of lung)
  10. Nasopharyngitis (inflammation of the nasopharynx)

40-49:

  1. Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection)
  2. Cardiac murmur (an heart sound in valve abnormality)
  3. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  4. Lung neoplasm malignant (cancer tumour of lung)
  5. Nasal polyps (masses that develop in the lining of the nose)
  6. Oedema peripheral (superficial swelling)
  7. Rhinitis allergic (inflammation of the nasal airways due to allergy)
  8. Sarcoidosis (an inflammatory disease that affects multiple organs in the body, but mostly the lungs and lymph glands)
  9. Total lung capacity increased
  10. Wheezing (a high-pitched whistling sound made while you breath)

50-59:

  1. Hyperkalaemia (damage to or disease of the kidney)
  2. Mitral valve incompetence (inefficient heart valve)
  3. Narcolepsy (brain's inability to regulate sleep-wake cycles normally)
  4. Nausea (feeling of having an urge to vomit)
  5. Nodal arrhythmia (an irregular heart beat originating from within the atrioventricular node)
  6. Oxygen saturation decreased
  7. Pulmonary oedema (fluid accumulation in the lungs)
  8. Upper respiratory tract infection
  9. Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)
  10. Aortic valve incompetence

60+:

  1. Dyspnoea (difficult or laboured respiration)
  2. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  3. Cough
  4. Diastolic dysfunction
  5. Disease recurrence
  6. Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
  7. Dyspnoea exertional (breathlessness or shortness of breath)
  8. Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
  9. Embolism venous (embolus may pass into the arterial system)
  10. Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs)

What are the existing conditions these people have? *

  1. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 22 people, 29.73%
  2. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 9 people, 12.16%
  3. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 7 people, 9.46%
  4. Pain: 6 people, 8.11%
  5. Constipation: 6 people, 8.11%
  6. Chest Pain: 6 people, 8.11%
  7. Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 6 people, 8.11%
  8. Iron Deficiency Anaemia: 5 people, 6.76%
  9. Hyperlipidaemia (presence of excess lipids in the blood): 5 people, 6.76%
  10. High Blood Pressure: 5 people, 6.76%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Formoterol fumarate and Combivent:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Formoterol fumarate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Combivent:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Formoterol fumarate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Combivent and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on formoterol fumarate and albuterol sulfate; ipratropium bromide (the active ingredients of Formoterol fumarate and Combivent, respectively), and Formoterol fumarate and Combivent (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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