Fosaprepitant and Metoclopramide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Fosaprepitant (fosaprepitant) and Metoclopramide (metoclopramide hydrochloride). Common drug interactions include mental status changes among females and white blood cell count decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Fosaprepitant and Metoclopramide. It is created by eHealthMe based on reports of 100 people who take the same drugs from the FDA, and is updated regularly.

What is Fosaprepitant?

Fosaprepitant has active ingredients of fosaprepitant. eHealthMe is studying from 1,178 Fosaprepitant users. Check the latest studies of Fosaprepitant.

What is Metoclopramide?

Metoclopramide has active ingredients of metoclopramide hydrochloride. It is often used in nausea. eHealthMe is studying from 81,263 Metoclopramide users. Check the latest studies of Metoclopramide.

On Jul, 14, 2026

100 people who take Fosaprepitant and Metoclopramide together, and have interactions are studied.

Fosaprepitant and Metoclopramide drug interactions.

What are the common drug interactions of Fosaprepitant and Metoclopramide, by gender? *:

female:

Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Muscular weakness (muscle weakness)
Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged)
Nephropathy toxic (damage to kidney due to toxins)
Neutropenia (an abnormally low number of neutrophils)
Organising pneumonia (pathologically by the presence in the distal air spaces of buds of granulation tissue)
Pain
Palpitations (feelings or sensations that your heart is pounding or racing)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Platelet count decreased

male:

White blood cell count decreased
Liver injury
Fatigue (feeling of tiredness)
Gastric disorder (disease of stomach)
Malignant neoplasm progression (cancer tumour came back)
Pneumonia
Vertigo
Colitis (inflammation of colon)
Anaemia (lack of blood)
Blood creatinine increased

What are the common drug interactions of Fosaprepitant and Metoclopramide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Blood creatinine increased
Colitis (inflammation of colon)
Sepsis (a severe blood infection that can lead to organ failure and death)
Sepsis syndrome (a clinical condition of blood infection)
Skin exfoliation (removal of the oldest dead skin cells)
Encephalopathy (functioning of the brain is affected by some agent or condition)
Enterobacter bacteraemia (enterobacter cloacae are nosocomial pathogens that can cause a range of infections such as bacteraemia, lower respiratory tract infection, skin)
Gastrointestinal mucosal exfoliation (mucous membrane comes out and new takes place in gastrointestinal tract)
Haematemesis (vomiting of blood)
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)

20-29:

n/a

30-39:

Febrile neutropenia (fever with reduced white blood cells)
Pyrexia (fever)

40-49:

Hypersensitivity
Infusion related reaction
Death
Transaminases increased
Akathisia (a movement disorder characterized by a feeling of inner restlessness)
Alopecia (absence of hair from areas of the body)
Hepatitis cholestatic (flow of bile from the liver is slowed or blocked)
Inflammation
Thrombosis mesenteric vessel (blood clot in mesenteric vein)
Drug ineffective

50-59:

Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Confusional state
Gastric cancer stage iii (the tumour has invaded nearby organs, such as the liver, colon, or spleen. cancer cells have not spread to lymph nodes or to distant organs)
Hypotension (abnormally low blood pressure)
Hypoxia (low oxygen in tissues)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Pyrexia (fever)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
White blood cell count decreased
Retinal tear

60+:

White blood cell count decreased
Liver injury
Malignant neoplasm progression (cancer tumour came back)
Neutropenia (an abnormally low number of neutrophils)
Alanine aminotransferase increased
Aspartate aminotransferase increased
Blood bilirubin increased
Colitis (inflammation of colon)
Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Diarrhoea

What are the existing conditions these people have? *

High Blood Pressure: 15 people, 15.00%
Nausea And Vomiting: 13 people, 13.00%
Stress And Anxiety: 12 people, 12.00%
Pain: 12 people, 12.00%
Lung Cancer - Non-Small Cell (lung cancer): 12 people, 12.00%
High Blood Cholesterol: 9 people, 9.00%
Diarrhea: 8 people, 8.00%
Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 7 people, 7.00%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 6 people, 6.00%
Oesophageal Squamous Cell Carcinoma (cancer that begins in flat cells lining the oesophagus): 6 people, 6.00%

* Approximation only. Some reports may have incomplete information.

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