Fosrenol and Prograf drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Fosrenol (lanthanum carbonate) and Prograf (tacrolimus). Common drug interactions include skin oedema among females and agranulocytosis among males.
The phase IV clinical study analyzes what interactions people have when they take Fosrenol and Prograf. It is created by eHealthMe based on reports of 45 people who take the same drugs from the FDA, and is updated regularly.
What is Fosrenol?
Fosrenol has active ingredients of lanthanum carbonate. eHealthMe is studying from 5,922 Fosrenol users. Check the latest studies of Fosrenol.
What is Prograf?
Prograf has active ingredients of tacrolimus. It is often used in kidney transplant. eHealthMe is studying from 42,230 Prograf users. Check the latest studies of Prograf.
45 people who take Fosrenol and Prograf together, and have interactions are studied.

What are the common drug interactions of Fosrenol and Prograf, by gender? *:
female:
- Skin oedema (swelling of skin)
- Skin plaque (red, scaly patches to appear on the skin)
- Vascular calcification (deposits of calcium in the blood vessels)
- Anaemia (lack of blood)
- Depression
- Skin discolouration (change of skin colour)
- Skin hypertrophy (skin cells enlarges)
- Syncope (loss of consciousness with an inability to maintain postural tone)
- Tachycardia (a heart rate that exceeds the range of 100 beats/min)
- Gingivitis (inflammation of gums)
male:
- Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
- Drug level increased
- Injury
- Mobility decreased (ability to move is reduced)
- Skin hypertrophy (skin cells enlarges)
- Extremity contracture (permanent shortening of a muscle or joint of arms and legs)
- Gait disturbance
- General physical health deterioration (weak health status)
- Hypertension (high blood pressure)
- Joint contracture (a permanent shortening of a muscle or joint)
What are the common drug interactions of Fosrenol and Prograf, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
- Aplasia pure red cell (type of anaemia affecting the precursors to red blood cells but not to white blood cells)
- Humoral immune defect (impairment of humoral immunity)
- Infection
- Therapeutic response decreased (less preventive response)
- Transplant rejection (a transplant material is not worked)
20-29:
- Large intestine perforation (hole in large intestine)
30-39:
- Pain
- Mobility decreased (ability to move is reduced)
- Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
- Abasia (inability to walk)
- Anxiety
- Emotional distress
- Fibrosis (formation of excess fibrous connective tissue in an organ or tissue)
- General physical health deterioration (weak health status)
- Injury
- Paronychia (infection in the tissues adjacent to a nail on a finger or toe)
40-49:
- Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
- Rectal haemorrhage (bleeding from anus)
- Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
- Pyrexia (fever)
- Transplant rejection (a transplant material is not worked)
- Iron deficiency anaemia
- Metrorrhagia (uterine bleeding at irregular intervals)
50-59:
- Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
- Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
- Pain
- Skin induration (an abnormally hard spot or area on the skin)
- Anxiety
- Emotional distress
- Gait disturbance
- Hypertension (high blood pressure)
- Injury
- Joint contracture (a permanent shortening of a muscle or joint)
60+:
- Nocardiosis (an infectious disease affecting either the lungs or whole body)
- Pneumonia
- Asthenia (weakness)
- Deformity (disfigurement)
- Depression
- Diarrhoea
- Dry skin
- Emotional distress
- Eosinophil count increased
- Exfoliative rash (scaly red generalized skin rash)
What are the existing conditions these people have? *
- High Blood Pressure: 14 people, 31.11%
- Hyperphosphataemia (electrolyte disturbance in which there is an abnormally elevated level of phosphate in the blood): 13 people, 28.89%
- Immunodeficiency Disorders: 10 people, 22.22%
- Pain: 5 people, 11.11%
- Diabetes: 5 people, 11.11%
- Kidney Transplant Rejection: 4 people, 8.89%
- Stable Angina (a constant chest pain): 3 people, 6.67%
- Pseudomonas Infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa): 3 people, 6.67%
- Insomnia (sleeplessness): 3 people, 6.67%
- Hyperlipidaemia (presence of excess lipids in the blood): 3 people, 6.67%
* Approximation only. Some reports may have incomplete information.
Do you take Fosrenol and Prograf?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Fosrenol and Prograf:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Fosrenol:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Prograf:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Fosrenol and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Prograf and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on lanthanum carbonate and tacrolimus (the active ingredients of Fosrenol and Prograf, respectively), and Fosrenol and Prograf (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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