Fragmin and Centrum drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Fragmin (dalteparin sodium) and Centrum (ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e). Common drug interactions include sinus headache among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Fragmin and Centrum. It is created by eHealthMe based on reports of 51 people who take the same drugs from the FDA, and is updated regularly.

What is Fragmin?

Fragmin has active ingredients of dalteparin sodium. It is often used in deep venous thrombosis. eHealthMe is studying from 11,999 Fragmin users. Check the latest studies of Fragmin.

What is Centrum?

Centrum has active ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e. It is often used in vitamin supplementation. eHealthMe is studying from 34,686 Centrum users. Check the latest studies of Centrum.

On Jul, 15, 2026

51 people who take Fragmin and Centrum together, and have interactions are studied.

What are the common drug interactions of Fragmin and Centrum, by gender? *:

female:

Sinus headache (headache caused by sinus infections)
Vitreous detachment (a condition of the eye in which the vitreous humour separates from the retina)
White blood cell count decreased
Abscess oral (abscess in the mouth)
Back pain
Chills (felling of cold)
Decreased appetite
Erythema nodosum (skin inflammation that results in reddish, painful, tender lumps most commonly located in the front of the legs below)
Haematochezia (passage of stools containing blood)
Haemorrhage (bleeding)

male:

Diarrhoea
Respiratory failure (inadequate gas exchange by the respiratory system)
Ecchymosis (a discoloration of the skin resulting from bleeding underneath)
Faecal occult blood positive
Gastric ulcer (stomach ulcer)
Herpes zoster
Hyperkeratosis (thickening of the outer layer of the skin)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Palmar-plantar erythrodysaesthesia syndrome (hand-foot syndrome)
Pruritus (severe itching of the skin)

What are the common drug interactions of Fragmin and Centrum, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Joint swelling
Pain
Purulent discharge (discharge that contains pus)
Rash
Skin warm
Subcutaneous abscess
Swelling
Abdominal pain upper
Abdominal pain
Drug ineffective

40-49:

Respiratory failure (inadequate gas exchange by the respiratory system)
Nephrocalcinosis (a condition in which calcium levels in the kidneys are increased)
Pancreatic disorder

50-59:

Tooth abscess (pus formation in tooth)
Asthenia (weakness)
Epistaxis (bleed from the nose)
Oropharyngeal pain
Pyrexia (fever)
Abdominal discomfort
Abdominal distension
Anaemia (lack of blood)
Anal fissure
Aphthous ulcer (mouth ulcer)

60+:

Diarrhoea
Herpes zoster
Decreased appetite
Ecchymosis (a discoloration of the skin resulting from bleeding underneath)
Faecal occult blood positive
Gastric ulcer (stomach ulcer)
Hyperkeratosis (thickening of the outer layer of the skin)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Hypertension (high blood pressure)
Injection site bruising

What are the existing conditions these people have? *

Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 25 people, 49.02%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 25 people, 49.02%
Abdominal Pain Upper: 21 people, 41.18%
Abdominal Pain: 10 people, 19.61%
Multiple Myeloma (cancer of the plasma cells): 7 people, 13.73%
Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 3 people, 5.88%
Pain: 3 people, 5.88%

* Approximation only. Some reports may have incomplete information.

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