Fragmin and Mesalamine drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Fragmin (dalteparin sodium) and Mesalamine (mesalamine). Common drug interactions include diarrhoea among females and cough among males.
The phase IV clinical study analyzes what interactions people have when they take Fragmin and Mesalamine. It is created by eHealthMe based on reports of 35 people who take the same drugs from the FDA, and is updated regularly.
What is Fragmin?
Fragmin has active ingredients of dalteparin sodium. It is often used in deep venous thrombosis. eHealthMe is studying from 11,999 Fragmin users. Check the latest studies of Fragmin.
What is Mesalamine?
Mesalamine has active ingredients of mesalamine. It is often used in ulcerative colitis. eHealthMe is studying from 28,053 Mesalamine users. Check the latest studies of Mesalamine.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
35 people who take Fragmin and Mesalamine together, and have interactions are studied.

What are the common drug interactions of Fragmin and Mesalamine, by gender? *:
female:
- Diarrhoea
- Vascular occlusion (sudden blockage of a blood vessel, usually with a clot)
- Neoplasm malignant (cancer tumour)
- Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
- Anaphylactic reaction (serious allergic reaction)
- Cerebral haemorrhage (bleeding within the brain)
- Drug ineffective
- Respiratory failure (inadequate gas exchange by the respiratory system)
- Abdominal pain upper
- Joint swelling
male:
- Cough
- Decreased appetite
- Injection site induration
- Injection site mass
- Injection site pain
- Nasopharyngitis (inflammation of the nasopharynx)
- Oropharyngeal pain
- Vomiting
- Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
- Weight decreased
What are the common drug interactions of Fragmin and Mesalamine, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Renal failure acute (rapid kidney dysfunction)
- Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
30-39:
- Abdominal discomfort
- Abdominal pain
- Cough
- Decreased appetite
- Diarrhoea
- Gastritis (inflammation of stomach)
- Haematemesis (vomiting of blood)
- Hypophagia (reduced food intake)
- Infection
- Injection site induration
40-49:
n/a
50-59:
- Diarrhoea
- Vascular occlusion (sudden blockage of a blood vessel, usually with a clot)
- Neoplasm malignant (cancer tumour)
- Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
- Cerebral haemorrhage (bleeding within the brain)
- Respiratory failure (inadequate gas exchange by the respiratory system)
- Large intestinal haemorrhage (bleeding in large intestine)
- Sensory loss (senses loss)
- Disease progression
- Paresis (a condition of muscular weakness)
60+:
- Herpes simplex hepatitis (inflammation of liver due to virus herpes simplex)
- Alanine aminotransferase increased
- Encephalopathy (functioning of the brain is affected by some agent or condition)
- Hepatic failure (liver failure)
- Infection susceptibility increased
- Decreased appetite
- Dyspnoea (difficult or laboured respiration)
- Gastritis (inflammation of stomach)
- Melaena (the passage of black, tarry stools)
- Nausea (feeling of having an urge to vomit)
What are the existing conditions these people have? *
- Peripheral Arterial Occlusive Disease (reproducible ischemic muscle pain): 7 people, 20.00%
- Neuroendocrine Tumor: 7 people, 20.00%
- Malignant Melanoma (skin cancer rises from melancytes): 7 people, 20.00%
- Diarrhea: 7 people, 20.00%
- Abdominal Pain Upper: 5 people, 14.29%
- Venous Thrombosis (blood clot (thrombus) that forms within a vein): 4 people, 11.43%
- Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 4 people, 11.43%
- Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs): 2 people, 5.71%
- Infection: 2 people, 5.71%
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 5.71%
* Approximation only. Some reports may have incomplete information.
Do you take Fragmin and Mesalamine?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Fragmin (11,999 reports)
- Mesalamine (28,053 reports)
Browse all drug interactions of Fragmin and Mesalamine:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Fragmin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Mesalamine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Fragmin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Mesalamine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Jacobsson H, Eriksen J, Karlén P, "Mesalazine-induced renal calculi", The American journal of case reports, 2015 Jan .
- Jacobsson H, Eriksen J, Karlén P, "Mesalazine-induced renal calculi", The American journal of case reports, 2015 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on dalteparin sodium and mesalamine (the active ingredients of Fragmin and Mesalamine, respectively), and Fragmin and Mesalamine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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