Frova and Pregabalin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Frova (frovatriptan succinate) and Pregabalin (pregabalin). Common drug interactions include urinary tract infection among females.

The phase IV clinical study analyzes what interactions people have when they take Frova and Pregabalin. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Frova?

Frova has active ingredients of frovatriptan succinate. It is often used in migraine. eHealthMe is studying from 2,100 Frova users. Check the latest studies of Frova.

What is Pregabalin?

Pregabalin has active ingredients of pregabalin. It is often used in fibromyalgia. eHealthMe is studying from 74,070 Pregabalin users. Check the latest studies of Pregabalin.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 28, 2026

14 people who take Frova and Pregabalin together, and have interactions are studied.

What are the common drug interactions of Frova and Pregabalin, by gender? *:

female:

Urinary tract infection
Dermatitis bullous (inflammation of the skin characterized by the presence of bullae which are filled with fluid)
Epistaxis (bleed from the nose)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Abdominal pain upper
Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
Blood pressure increased
Cataract (clouding of the lens inside the eye)
Erythema (redness of the skin)
Infection

male:

n/a

What are the common drug interactions of Frova and Pregabalin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Dermatitis bullous (inflammation of the skin characterized by the presence of bullae which are filled with fluid)
Drug ineffective
Dyspnoea (difficult or laboured respiration)
Eye pruritus (eye itching)
Urinary tract infection
Urticaria chronic (long lasting rash of round, red welts on the skin that itch intensely)
Fatigue (feeling of tiredness)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Stupor (lack of critical cognitive function and level of consciousness)

40-49:

Cough
Pulmonary fibrosis (formation or development of excess fibrous connective tissue (fibrosis) in the lungs)

50-59:

Pruritus (severe itching of the skin)
Pulmonary embolism (blockage of the main artery of the lung)
Tooth infection
Urinary tract infection
Abdominal pain upper
Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
Blood pressure increased
Cataract (clouding of the lens inside the eye)
Erythema (redness of the skin)
Infection

60+:

Anaemia (lack of blood)
Epistaxis (bleed from the nose)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)

What are the existing conditions these people have? *

Depression: 4 people, 28.57%
Wheezing (a high-pitched whistling sound made while you breath): 3 people, 21.43%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 3 people, 21.43%
Psychiatric Symptom: 3 people, 21.43%
Infectious Mononucleosis (infection usually caused by the epstein-barr virus): 3 people, 21.43%
Dyspnea (difficult or laboured breathing): 3 people, 21.43%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 21.43%
Immunodeficiency Common Variable: 2 people, 14.29%
Asthma: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

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