Frova and Spiriva drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Frova (frovatriptan succinate) and Spiriva (tiotropium bromide monohydrate). Common drug interactions include hyperhidrosis among females.

The phase IV clinical study analyzes what interactions people have when they take Frova and Spiriva. It is created by eHealthMe based on reports of 29 people who take the same drugs from the FDA, and is updated regularly.

What is Frova?

Frova has active ingredients of frovatriptan succinate. It is often used in migraine. eHealthMe is studying from 2,100 Frova users. Check the latest studies of Frova.

What is Spiriva?

Spiriva has active ingredients of tiotropium bromide monohydrate. It is often used in chronic obstructive pulmonary disease. eHealthMe is studying from 156,666 Spiriva users. Check the latest studies of Spiriva.

On Jul, 27, 2026

29 people who take Frova and Spiriva together, and have interactions are studied.

What are the common drug interactions of Frova and Spiriva, by gender? *:

female:

Hyperhidrosis (abnormally increased sweating)
Nausea (feeling of having an urge to vomit)
Temperature intolerance (inability to go in temperature)
Cough
Ear pain
Insomnia (sleeplessness)
Mobility decreased (ability to move is reduced)
Pyrexia (fever)
Vomiting
Wheezing (a high-pitched whistling sound made while you breath)

male:

n/a

What are the common drug interactions of Frova and Spiriva, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Dyspnoea (difficult or laboured respiration)
Facial pain
Fatigue (feeling of tiredness)
Headache (pain in head)
Meningitis viral (viral inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges)
Paranasal sinus hypersecretion
Pyrexia (fever)
Sinusitis (inflammation of sinus)
Wheezing (a high-pitched whistling sound made while you breath)

30-39:

Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Anxiety
Arthralgia (joint pain)
Balance disorder
Bladder spasm
Breast abscess
Breast cellulitis (spreading, acute inflammation of beast skin)
Breast tenderness
Chest pain
Colonic polyp (extra part of colon tissue grow in intestine)

40-49:

Respiratory tract infection
Rhinorrhoea (watery mucus discharge from the nose)
Seasonal allergy (allergic condition due to certain season)
Sinusitis (inflammation of sinus)
Somnolence (a state of near-sleep, a strong desire for sleep)
Sputum discoloured
Throat tightness
Tinnitus (a ringing in the ears)
Weight decreased
Wheezing (a high-pitched whistling sound made while you breath)

50-59:

Arthralgia (joint pain)
Body height decreased
Bone disorder
Burns second degree
Colitis (inflammation of colon)
Colitis ulcerative (inflammation of colon with ulcer)
Connective tissue disorder (any disease that has the connective tissues of the body)
Constipation
Diarrhoea
Dyspepsia (indigestion)

60+:

Pneumonia

What are the existing conditions these people have? *

Asthma: 20 people, 68.97%
Lung Disorder (lung disease): 15 people, 51.72%
Hypoaesthesia (reduced sense of touch or sensation): 15 people, 51.72%
Sinusitis (inflammation of sinus): 10 people, 34.48%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 10 people, 34.48%
Pain: 6 people, 20.69%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 17.24%
Multiple Allergies (allergy to multiple agents): 3 people, 10.34%
High Blood Pressure: 3 people, 10.34%
Depression: 3 people, 10.34%

* Approximation only. Some reports may have incomplete information.

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