Gabapentin and Onivyde drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Gabapentin (gabapentin) and Onivyde (irinotecan hydrochloride). Common drug interactions include hypokalaemia among females and diarrhoea haemorrhagic among males.

The phase IV clinical study analyzes what interactions people have when they take Gabapentin and Onivyde. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Gabapentin?

Gabapentin has active ingredients of gabapentin. It is often used in neuralgia. eHealthMe is studying from 322,983 Gabapentin users. Check the latest studies of Gabapentin.

What is Onivyde?

Onivyde has active ingredients of irinotecan hydrochloride. eHealthMe is studying from 1,198 Onivyde users. Check the latest studies of Onivyde.

On Jul, 27, 2026

21 people who take Gabapentin and Onivyde together, and have interactions are studied.

Gabapentin and Onivyde drug interactions.

What are the common drug interactions of Gabapentin and Onivyde, by gender? *:

female:

Hypokalaemia (low potassium)
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
Abdominal discomfort
Diarrhoea
Vomiting
Weight decreased
Nausea (feeling of having an urge to vomit)
Decreased appetite
Dyspnoea (difficult or laboured respiration)
Pneumonia

male:

Diarrhoea haemorrhagic (bloody diarrhoea)
Disease progression
Oropharyngeal discomfort (pain or irritation of oropharynx)
Pruritus (severe itching of the skin)
Pyrexia (fever)
Sepsis (a severe blood infection that can lead to organ failure and death)
Vomiting
Ascites (accumulation of fluid in the abdominal cavity)
Colitis (inflammation of colon)
Febrile neutropenia (fever with reduced white blood cells)

What are the common drug interactions of Gabapentin and Onivyde, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Abdominal discomfort
Colitis (inflammation of colon)
Febrile neutropenia (fever with reduced white blood cells)
Abdominal pain
Nausea (feeling of having an urge to vomit)
Pyrexia (fever)
Vomiting

20-29:

Sepsis (a severe blood infection that can lead to organ failure and death)

30-39:

n/a

40-49:

Decreased appetite
Pneumonia
Dyspnoea (difficult or laboured respiration)
Pyrexia (fever)

50-59:

Ascites (accumulation of fluid in the abdominal cavity)
Dyspnoea (difficult or laboured respiration)
Erythema (redness of the skin)
Flushing (the warm, red condition of human skin)
Oropharyngeal discomfort (pain or irritation of oropharynx)
Pruritus (severe itching of the skin)

60+:

Vomiting
Abdominal discomfort
Haematochezia (passage of stools containing blood)
Nausea (feeling of having an urge to vomit)
Hypokalaemia (low potassium)
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
Abdominal pain
Chills (felling of cold)
Colitis (inflammation of colon)
Dizziness

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 28.57%
Flatulence (flatus expelled through the anus): 5 people, 23.81%
Depression: 4 people, 19.05%
Diarrhea: 4 people, 19.05%
Sleep Disorder: 3 people, 14.29%
Sarcoma (rare cancers that develop in the muscle, bone, nerves, cartilage, tendons, blood vessels and the fatty and fibrous tissues): 3 people, 14.29%
Abdominal Pain Upper: 3 people, 14.29%
Neuropathy Peripheral (surface nerve damage): 3 people, 14.29%
Nausea And Vomiting: 3 people, 14.29%
Diabetes: 3 people, 14.29%

* Approximation only. Some reports may have incomplete information.

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