Gammagard and Spironolactone and hydrochlorothiazide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Gammagard (immune globulin) and Spironolactone and hydrochlorothiazide (hydrochlorothiazide; spironolactone). Common drug interactions include mental status changes among females and hypotension among males.

The phase IV clinical study analyzes what interactions people have when they take Gammagard and Spironolactone and hydrochlorothiazide. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Gammagard?

Gammagard has active ingredients of immune globulin. eHealthMe is studying from 8,947 Gammagard users. Check the latest studies of Gammagard.

What is Spironolactone and hydrochlorothiazide?

Spironolactone and hydrochlorothiazide has active ingredients of hydrochlorothiazide; spironolactone. It is often used in high blood pressure. eHealthMe is studying from 567 Spironolactone and hydrochlorothiazide users. Check the latest studies of Spironolactone and hydrochlorothiazide.



On Jul, 08, 2026

11 people who take Gammagard and Spironolactone and hydrochlorothiazide together, and have interactions are studied.

Gammagard and Spironolactone and hydrochlorothiazide drug interactions.

What are the common drug interactions of Gammagard and Spironolactone And Hydrochlorothiazide, by gender? *:

female:

  1. Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
  2. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  3. Death
  4. Decreased appetite
  5. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
  6. Malaise (a feeling of general discomfort or uneasiness)
  7. Weight fluctuation
  8. Ammonia increased
  9. Ascites (accumulation of fluid in the abdominal cavity)
  10. Blood pressure decreased

male:

  1. Hypotension (abnormally low blood pressure)
  2. Infusion related reaction
  3. Deafness
  4. Infusion site erythema (reddening of the skin at infusion site)
  5. Oxygen saturation decreased
  6. Pulmonary hypertension (increase in blood pressure in the lung artery)
  7. Respiratory distress (difficulty in breathing)

What are the common drug interactions of Gammagard and Spironolactone And Hydrochlorothiazide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Infusion site erythema (reddening of the skin at infusion site)
  2. Oxygen saturation decreased
  3. Pulmonary hypertension (increase in blood pressure in the lung artery)
  4. Respiratory distress (difficulty in breathing)

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

  1. Sinusitis (inflammation of sinus)
  2. Ammonia increased
  3. Hydrocephalus (water on the brain)
  4. Hypersensitivity
  5. Influenza
  6. Infusion related reaction
  7. Pruritus (severe itching of the skin)
  8. Pseudomonas infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa)
  9. Fall
  10. Laryngitis (inflammation of the larynx)

What are the existing conditions these people have? *

  1. Immunodeficiency Common Variable: 4 people, 36.36%
  2. Chronic Inflammatory Demyelinating Polyradiculoneuropathy (long lasting infection of nerves outside brain and spinal cord): 2 people, 18.18%
  3. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 1 person, 9.09%
  4. Myasthenia Gravis (a chronic condition that causes muscles to tire and weaken easily): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Gammagard and Spironolactone and hydrochlorothiazide?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Gammagard and Spironolactone and hydrochlorothiazide:

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Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Gammagard:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Spironolactone and hydrochlorothiazide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Gammagard and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Spironolactone and hydrochlorothiazide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on immune globulin and hydrochlorothiazide; spironolactone (the active ingredients of Gammagard and Spironolactone and hydrochlorothiazide, respectively), and Gammagard and Spironolactone and hydrochlorothiazide (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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