Garlic and Colace drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Garlic (allium sativum) and Colace (docusate ). Common drug interactions include macular hole among females and activities of daily living impaired among males.

The phase IV clinical study analyzes what interactions people have when they take Garlic and Colace. It is created by eHealthMe based on reports of 44 people who take the same drugs from the FDA, and is updated regularly.

What is Garlic?

Garlic has active ingredients of allium sativum. It is often used in heart health. eHealthMe is studying from 2,715 Garlic users. Check the latest studies of Garlic.

What is Colace?

Colace has active ingredients of docusate . It is often used in constipation. eHealthMe is studying from 41,841 Colace users. Check the latest studies of Colace.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 26, 2026

44 people who take Garlic and Colace together, and have interactions are studied.

Garlic and Colace drug interactions.

What are the common drug interactions of Garlic and Colace, by gender? *:

female:

  1. Macular hole (small break in the macula, the central area of the retina)
  2. Metastases to bone (cancer spreads to bone)
  3. Metastases to liver (cancer spreads to liver)
  4. Mouth ulceration (mouth ulcers)
  5. Nasopharyngitis (inflammation of the nasopharynx)
  6. Nocturia (the need to get up in the night to urinate)
  7. Oesophageal stenosis (narrowing of oesophagus)
  8. Osteonecrosis of jaw (death of bone of jaw)
  9. Osteopenia (a condition where bone mineral density is lower than normal)
  10. Osteoporosis (bones weak and more likely to break)

male:

  1. Activities of daily living impaired
  2. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  3. Influenza
  4. Malaise (a feeling of general discomfort or uneasiness)
  5. Renal failure (kidney dysfunction)
  6. Speech disorder
  7. Cough
  8. Diabetic coma
  9. Epistaxis (bleed from the nose)
  10. Hypotension (abnormally low blood pressure)

What are the common drug interactions of Garlic and Colace, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Activities of daily living impaired
  2. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  3. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  4. Coma (state of unconsciousness lasting more than six hours)
  5. Gait disturbance
  6. Hallucination (an experience involving the perception of something not present)
  7. Hemiplegia (paralysis of one side of the body)
  8. Influenza
  9. Malaise (a feeling of general discomfort or uneasiness)
  10. Renal failure (kidney dysfunction)

40-49:

  1. Asthma
  2. Blood pressure decreased
  3. Respiration (transport of oxygen from the outside air to the cells within tissues)
  4. Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
  5. Somnolence (a state of near-sleep, a strong desire for sleep)
  6. Weight increased
  7. Bipolar i disorder (mood disorder that is characterized by at least one manic or mixed episode)
  8. Confusional state
  9. Lethargy (tiredness)
  10. Obstructive sleep apnoea syndrome (frequent pauses in breathing during sleep usually accompanied by loud snoring)

50-59:

  1. Back disorder
  2. Benign neoplasm of adrenal gland (benign (non-cancerous) tumours of the adrenal gland)
  3. Blindness
  4. Bone disorder
  5. Bruxism (habitual grinding of the teeth, typically during sleep)
  6. Cataract (clouding of the lens inside the eye)
  7. Central nervous system lesion (an abnormality in tissue of brain or spinal cord)
  8. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  9. Cough
  10. Death

60+:

  1. Diarrhoea
  2. Cough
  3. Pain
  4. Pharyngitis streptococcal (inflammation of the pharynx caused by infection from. streptococcus)
  5. Activities of daily living impaired
  6. Acute myocardial infarction (acute heart attack)
  7. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  8. Aortic valve sclerosis (narrowing of the aortic valve)
  9. Aortic valve stenosis (narrowing of the aortic valve)
  10. Appetite disorder (abnormal eating habits)

What are the existing conditions these people have? *

  1. Pain: 11 people, 25.00%
  2. Multiple Myeloma (cancer of the plasma cells): 8 people, 18.18%
  3. Arthritis (form of joint disorder that involves inflammation of one or more joints): 5 people, 11.36%
  4. Seasonal Allergy (allergic condition due to certain season): 4 people, 9.09%
  5. Wheezing (a high-pitched whistling sound made while you breath): 3 people, 6.82%
  6. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 6.82%
  7. Renal Cell Carcinoma (a kidney cancer): 3 people, 6.82%
  8. Nausea (feeling of having an urge to vomit): 3 people, 6.82%
  9. Infection: 3 people, 6.82%
  10. High Blood Pressure: 3 people, 6.82%

* Approximation only. Some reports may have incomplete information.

Do you take Garlic and Colace?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Garlic and Colace:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Garlic:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Colace:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Garlic and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Colace and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on allium sativum and docusate (the active ingredients of Garlic and Colace, respectively), and Garlic and Colace (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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