Gemcitabine and Dipyrone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Gemcitabine (gemcitabine) and Dipyrone (metamizole). Common drug interactions include pleural effusion among females and blood creatinine increased among males.

The phase IV clinical study analyzes what interactions people have when they take Gemcitabine and Dipyrone. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Gemcitabine?

Gemcitabine has active ingredients of gemcitabine. eHealthMe is studying from 31,337 Gemcitabine users. Check the latest studies of Gemcitabine.

What is Dipyrone?

Dipyrone has active ingredients of metamizole. eHealthMe is studying from 1,876 Dipyrone users. Check the latest studies of Dipyrone.



On Jul, 18, 2026

27 people who take Gemcitabine and Dipyrone together, and have interactions are studied.

Gemcitabine and Dipyrone drug interactions.

What are the common drug interactions of Gemcitabine and Dipyrone, by gender? *:

female:

  1. Pleural effusion (water on the lungs)
  2. Overdose
  3. Vasculitis (inflammation of a blood vessel or blood vessels)
  4. Gastric ulcer (stomach ulcer)
  5. Glomerulonephropathy (any noninflammatory disease of the renal glomeruli)
  6. Intussusception
  7. Pyrexia (fever)
  8. Thrombotic microangiopathy (a pathology that results in thrombosis in capillaries and arterioles, due to an endothelial injury)
  9. Ileus (a painful obstruction of the ileum or other part of the intestine)
  10. Lung disorder (lung disease)

male:

  1. Blood creatinine increased
  2. C-reactive protein increased
  3. Pleural effusion (water on the lungs)
  4. Pneumonia
  5. Respiratory syncytial virus infection (viral disease of respiratory system)
  6. Septic shock (shock due to blood infection)
  7. Vomiting
  8. Weight increased
  9. Acute myocardial infarction (acute heart attack)
  10. Blood culture positive

What are the common drug interactions of Gemcitabine and Dipyrone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Colitis (inflammation of colon)

40-49:

  1. Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
  2. Metastases to brain (cancer spreads to brain)

50-59:

  1. Gastric ulcer (stomach ulcer)
  2. Ileus (a painful obstruction of the ileum or other part of the intestine)
  3. Vomiting
  4. Acute myocardial infarction (acute heart attack)
  5. Arthralgia (joint pain)
  6. Diarrhoea
  7. Dizziness
  8. Dysgeusia (disorder of the sense of taste)
  9. Fatigue (feeling of tiredness)
  10. Myalgia (muscle pain)

60+:

  1. Pleural effusion (water on the lungs)
  2. Overdose
  3. Blood creatinine increased
  4. Dehydration (dryness resulting from the removal of water)
  5. Diarrhoea
  6. Dysphagia (a condition in which swallowing is difficult or painful)
  7. Gram stain positive
  8. Ileus (a painful obstruction of the ileum or other part of the intestine)
  9. Lung disorder (lung disease)
  10. Neoplasm malignant (cancer tumour)

What are the existing conditions these people have? *

  1. Pancreatic Carcinoma (pancreatic cancer): 5 people, 18.52%
  2. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 14.81%
  3. Pain: 4 people, 14.81%
  4. Indigestion: 4 people, 14.81%
  5. Pancreatic Carcinoma Metastatic (pancreatic cancer- metastatic): 3 people, 11.11%
  6. Lung Cancer - Non-Small Cell (lung cancer): 3 people, 11.11%
  7. Tumor Pain: 2 people, 7.41%
  8. High Blood Pressure: 2 people, 7.41%
  9. Abdominal Pain: 2 people, 7.41%
  10. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 2 people, 7.41%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Gemcitabine and Dipyrone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Gemcitabine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Dipyrone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Gemcitabine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Dipyrone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on gemcitabine and metamizole (the active ingredients of Gemcitabine and Dipyrone, respectively), and Gemcitabine and Dipyrone (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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