Gemcitabine and Nplate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Gemcitabine (gemcitabine) and Nplate (romiplostim). Common drug interactions include thrombocytopenia among females and cerebrovascular accident among males.

The phase IV clinical study analyzes what interactions people have when they take Gemcitabine and Nplate. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Gemcitabine?

Gemcitabine has active ingredients of gemcitabine. eHealthMe is studying from 31,337 Gemcitabine users. Check the latest studies of Gemcitabine.

What is Nplate?

Nplate has active ingredients of romiplostim. It is often used in idiopathic thrombocytopenic purpura (itp). eHealthMe is studying from 17,850 Nplate users. Check the latest studies of Nplate.



On Aug, 11, 2026

13 people who take Gemcitabine and Nplate together, and have interactions are studied.

Gemcitabine and Nplate drug interactions.

What are the common drug interactions of Gemcitabine and Nplate, by gender? *:

female:

  1. Thrombocytopenia (decrease of platelets in blood)
  2. Drug ineffective
  3. Platelet count decreased
  4. Hospitalisation
  5. Breast cancer
  6. Death
  7. Renal impairment (severely reduced kidney function)

male:

  1. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  2. Drug ineffective
  3. Gingivitis (inflammation of gums)
  4. Neutropenia (an abnormally low number of neutrophils)
  5. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  6. Thrombocytopenia (decrease of platelets in blood)
  7. Toothache (tooth pain)
  8. Fungal infection
  9. Metastases to adrenals (cancer spreads to adrenal gland of kidney)
  10. Metastases to bone (cancer spreads to bone)

What are the common drug interactions of Gemcitabine and Nplate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Thrombocytopenia (decrease of platelets in blood)
  2. Drug ineffective
  3. Platelet count decreased
  4. Hospitalisation
  5. Breast cancer

40-49:

  1. Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
  2. Drug ineffective
  3. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)

50-59:

n/a

60+:

  1. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  2. Drug ineffective
  3. Gingivitis (inflammation of gums)
  4. Neutropenia (an abnormally low number of neutrophils)
  5. Renal impairment (severely reduced kidney function)
  6. Thrombocytopenia (decrease of platelets in blood)
  7. Toothache (tooth pain)
  8. Fungal infection
  9. Metastases to adrenals (cancer spreads to adrenal gland of kidney)
  10. Metastases to bone (cancer spreads to bone)

What are the existing conditions these people have? *

  1. Idiopathic Thrombocytopenic Purpura (bleeding disorder in which the immune system destroys platelets, which are necessary for normal blood clotting): 10 people, 76.92%
  2. Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 1 person, 7.69%
  3. Lung Adenocarcinoma (a form of non-small cell lung cancer): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Gemcitabine and Nplate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Gemcitabine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Nplate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Gemcitabine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Nplate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on gemcitabine and romiplostim (the active ingredients of Gemcitabine and Nplate, respectively), and Gemcitabine and Nplate (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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