Gemfibrozil and Evoxac drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Gemfibrozil (gemfibrozil) and Evoxac (cevimeline hydrochloride). Common drug interactions include muscle spasms among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Gemfibrozil and Evoxac. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Gemfibrozil?

Gemfibrozil has active ingredients of gemfibrozil. It is often used in high blood cholesterol. eHealthMe is studying from 18,213 Gemfibrozil users. Check the latest studies of Gemfibrozil.

What is Evoxac?

Evoxac has active ingredients of cevimeline hydrochloride. It is often used in sjogren syndrome. eHealthMe is studying from 2,028 Evoxac users. Check the latest studies of Evoxac.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 03, 2026

12 people who take Gemfibrozil and Evoxac together, and have interactions are studied.

Gemfibrozil and Evoxac drug interactions.

What are the common drug interactions of Gemfibrozil and Evoxac, by gender? *:

female:

  1. Muscle spasms (muscle contraction)
  2. Obstructive airways disorder (a progressive disease that makes it hard to breathe)
  3. Oral candidiasis (fungal infection of mouth)
  4. Osteopenia (a condition where bone mineral density is lower than normal)
  5. Pulmonary mass
  6. Pyrexia (fever)
  7. Restless legs syndrome (a powerful urge to move your legs)
  8. Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
  9. Tremor (trembling or shaking movements in one or more parts of your body)
  10. Visual impairment

male:

  1. Anaemia (lack of blood)
  2. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)

What are the common drug interactions of Gemfibrozil and Evoxac, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

  1. Chronic kidney disease
  2. Contusion (a type of hematoma of tissue in which capillaries)
  3. Oral candidiasis (fungal infection of mouth)
  4. Osteopenia (a condition where bone mineral density is lower than normal)
  5. Pulmonary mass
  6. Pyrexia (fever)
  7. Restless legs syndrome (a powerful urge to move your legs)
  8. Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
  9. Tremor (trembling or shaking movements in one or more parts of your body)
  10. Visual impairment

What are the existing conditions these people have? *

  1. Dry Mouth: 9 people, 75.00%
  2. High Blood Pressure: 8 people, 66.67%
  3. Anaemia (lack of blood): 7 people, 58.33%
  4. Stress And Anxiety: 7 people, 58.33%
  5. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 58.33%
  6. Depression: 7 people, 58.33%
  7. Back Pain: 7 people, 58.33%
  8. Diarrhea: 6 people, 50.00%
  9. Seizures (abnormal excessive or synchronous neuronal activity in the brain): 6 people, 50.00%
  10. Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 6 people, 50.00%

* Approximation only. Some reports may have incomplete information.

Do you take Gemfibrozil and Evoxac?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Gemfibrozil and Evoxac:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Gemfibrozil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Evoxac:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Gemfibrozil and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Evoxac and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on gemfibrozil and cevimeline hydrochloride (the active ingredients of Gemfibrozil and Evoxac, respectively), and Gemfibrozil and Evoxac (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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