Gemfibrozil and Prempro drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Gemfibrozil (gemfibrozil) and Prempro (estrogens, conjugated; medroxyprogesterone acetate). Common drug interactions include breast mass among females.

The phase IV clinical study analyzes what interactions people have when they take Gemfibrozil and Prempro. It is created by eHealthMe based on reports of 45 people who take the same drugs from the FDA, and is updated regularly.

What is Gemfibrozil?

Gemfibrozil has active ingredients of gemfibrozil. It is often used in high blood cholesterol. eHealthMe is studying from 18,213 Gemfibrozil users. Check the latest studies of Gemfibrozil.

What is Prempro?

Prempro has active ingredients of estrogens, conjugated; medroxyprogesterone acetate. It is often used in menopause. eHealthMe is studying from 42,950 Prempro users. Check the latest studies of Prempro.

On Jul, 09, 2026

45 people who take Gemfibrozil and Prempro together, and have interactions are studied.

Gemfibrozil and Prempro drug interactions.

What are the common drug interactions of Gemfibrozil and Prempro, by gender? *:

female:

Breast mass
Breast cancer female
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Colonic polyp (extra part of colon tissue grow in intestine)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Diverticulum intestinal (a pouch that is attached to the first part of the small intestine)
Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs)
Haemorrhoid operation
Hot flush (sudden feelings of heat)
Hypergammaglobulinaemia (elevated levels of gamma globulin)

male:

n/a

What are the common drug interactions of Gemfibrozil and Prempro, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Iga nephropathy (kidney disease- condition prevents the kidneys from filtering waste)
Pain
Renal failure chronic (long lasting kidney dysfunction)

50-59:

Nightmare (unpleasant dream)
Renal failure (kidney dysfunction)
Renal impairment (severely reduced kidney function)
Renal injury (kidney injury)
Stress
Tooth infection
Toothache (tooth pain)
Trigger finger
Venous valve ruptured
Breast mass

60+:

Breast cancer female
Chronic kidney disease
Hypoaesthesia (reduced sense of touch or sensation)
Hypotension (abnormally low blood pressure)
Infection
Menometrorrhagia (a condition in which prolonged or excessive uterine bleeding occurs irregularly and more frequently than normal)
Muscle weakness (a lack of muscle strength)
Myalgia (muscle pain)
Precerebral artery occlusion (precerebral artery blockage)
Pulmonary embolism (blockage of the main artery of the lung)

What are the existing conditions these people have? *

High Blood Pressure: 7 people, 15.56%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 5 people, 11.11%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 11.11%
Depression: 4 people, 8.89%
Menopausal Symptoms: 3 people, 6.67%
Hot Flush (sudden feelings of heat): 3 people, 6.67%

* Approximation only. Some reports may have incomplete information.

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