Genotropin and Ibu drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Genotropin (somatropin recombinant) and Ibu (ibuprofen). Common drug interactions include intracranial aneurysm among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Genotropin and Ibu. It is created by eHealthMe based on reports of 95 people who take the same drugs from the FDA, and is updated regularly.

What is Genotropin?

Genotropin has active ingredients of somatropin recombinant. It is often used in growth hormone deficiency. eHealthMe is studying from 41,924 Genotropin users. Check the latest studies of Genotropin.

What is Ibu?

Ibu has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 246,531 Ibu users. Check the latest studies of Ibu.

On Aug, 02, 2026

95 people who take Genotropin and Ibu together, and have interactions are studied.

What are the common drug interactions of Genotropin and Ibu, by gender? *:

female:

Intracranial aneurysm (bulging, weak area in the wall of a cranial artery)
Weight increased
Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)
Alanine aminotransferase increased
Aspartate aminotransferase increased
Asthenia (weakness)
Blood pressure decreased
Emotional disorder
Hepatic adenoma (benign liver tumour)
Hepatic steatosis (fatty liver disease)

male:

Fatigue (feeling of tiredness)
Malaise (a feeling of general discomfort or uneasiness)
Hypotension (abnormally low blood pressure)
Asthenia (weakness)
Constipation
Hyperkeratosis (thickening of the outer layer of the skin)
Muscle spasms (muscle contraction)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Neck pain
Peripheral swelling

What are the common drug interactions of Genotropin and Ibu, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Burns third degree
Decubitus ulcer (a chronic ulcer of the skin caused by prolonged pressure on it)
Hypertonic bladder (bladder-storage function that causes a sudden urge to urinate)
Renal cyst (kidney cyst)
Agitation (state of anxiety or nervous excitement)
Arthralgia (joint pain)
Pain in extremity
Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Intracranial pressure increased (high pressure inside the skull and thus in the brain tissue and cerebrospinal fluid)

10-19:

Fatigue (feeling of tiredness)
Autoimmune thyroiditis (form of thyroiditis associated with an autoimmune disease)
Sinus disorder (disease of sinus)
Drug ineffective
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Atelectasis (partial or complete collapse of the lung)
Histiocytosis haematophagic
Rash erythematous (redness of the skin)
Alanine aminotransferase increased
Aspartate aminotransferase increased

20-29:

n/a

30-39:

Asthenia (weakness)
Gastric disorder (disease of stomach)
Pulmonary embolism (blockage of the main artery of the lung)
Somnolence (a state of near-sleep, a strong desire for sleep)

40-49:

Nasopharyngitis (inflammation of the nasopharynx)
Fatigue (feeling of tiredness)
Hyperkeratosis (thickening of the outer layer of the skin)
Muscle spasms (muscle contraction)
Musculoskeletal discomfort (discomfort in the body's muscles, joints, tendons, ligaments and nerves)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Neck pain
Pain in extremity
Peripheral swelling
Tremor (trembling or shaking movements in one or more parts of your body)

50-59:

Nausea (feeling of having an urge to vomit)
Chills (felling of cold)
Discomfort
Tremor (trembling or shaking movements in one or more parts of your body)
Injection site haemorrhage (bleeding from injection site)
Intracranial aneurysm (bulging, weak area in the wall of a cranial artery)
Poor quality sleep
Pyrexia (fever)
Blindness
Eye disorder

60+:

Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
Haematemesis (vomiting of blood)
Weight increased
Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)
Adrenocortical insufficiency acute (suddenly adrenal glands do not produce adequate amounts of steroid hormones)
Dehydration (dryness resulting from the removal of water)
Drug ineffective
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Bile duct cancer
Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)

What are the existing conditions these people have? *

Hypopituitarism (diminished hormone secretion by the pituitary gland, causing dwarfism in children and premature aging in adults): 16 people, 16.84%
Headache (pain in head): 13 people, 13.68%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 7.37%
Depression: 6 people, 6.32%
Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 6 people, 6.32%
High Blood Pressure: 5 people, 5.26%
Failure To Thrive (inadequate weight gain and physical growth in children): 5 people, 5.26%
Bone Disorder: 5 people, 5.26%
Adrenocortical Insufficiency Acute (suddenly adrenal glands do not produce adequate amounts of steroid hormones): 5 people, 5.26%

* Approximation only. Some reports may have incomplete information.

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