Genotropin and Zide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Genotropin (somatropin recombinant) and Zide (hydrochlorothiazide). Common drug interactions include renal impairment among females and cerebrovascular accident among males.

The phase IV clinical study analyzes what interactions people have when they take Genotropin and Zide. It is created by eHealthMe based on reports of 61 people who take the same drugs from the FDA, and is updated regularly.

What is Genotropin?

Genotropin has active ingredients of somatropin recombinant. It is often used in growth hormone deficiency. eHealthMe is studying from 41,924 Genotropin users. Check the latest studies of Genotropin.

What is Zide?

Zide has active ingredients of hydrochlorothiazide. It is often used in high blood pressure. eHealthMe is studying from 183,246 Zide users. Check the latest studies of Zide.

On Jul, 11, 2026

61 people who take Genotropin and Zide together, and have interactions are studied.

What are the common drug interactions of Genotropin and Zide, by gender? *:

female:

Renal impairment (severely reduced kidney function)
Renal osteodystrophy (a bone disease occurs when the kidneys fail to maintain the proper levels of calcium and phosphorus in the blood)
Salmonellosis (an infection with salmonella bacteria)
Swelling face
Thrombosis (formation of a blood clot inside a blood vessel)
Thyroid cancer
Nausea (feeling of having an urge to vomit)
Insomnia (sleeplessness)
Pain
Drug ineffective

male:

Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Alanine aminotransferase increased
Headache (pain in head)
Joint swelling
Meningitis bacterial (bacterial inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges)
Nausea (feeling of having an urge to vomit)
Neck pain
Oedema peripheral (superficial swelling)
Pyrexia (fever)
White blood cell count increased

What are the common drug interactions of Genotropin and Zide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Emotional disorder
Headache (pain in head)
Hot flush (sudden feelings of heat)

10-19:

Headache (pain in head)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Benign intracranial hypertension (benign intracranial hypertension (bih) is a headache syndrome)
Abdominal pain upper
Arthralgia (joint pain)
Dizziness postural
Injection site bruising
Lyme disease (a bacterial infection that is spread to humans by infected ticks)
Papilloedema (optic disc swelling)

20-29:

Arthralgia (joint pain)
Face oedema (swelling of face)
Joint swelling
Oedema peripheral (superficial swelling)

30-39:

Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Pulmonary embolism (blockage of the main artery of the lung)

40-49:

Agitation (state of anxiety or nervous excitement)
Asthenia (weakness)
Bradyphrenia (neurological term referring to the slowness of thought common to many disorders of the brain)
Photosensitivity reaction
Pulmonary thrombosis (scarring in the lungs)
Thrombosis (formation of a blood clot inside a blood vessel)

50-59:

Nausea (feeling of having an urge to vomit)
Insomnia (sleeplessness)
Drug ineffective
Fatigue (feeling of tiredness)
Injection site bruising
Appetite disorder (abnormal eating habits)
Chills (felling of cold)
Discomfort
Fluid retention (an abnormal accumulation of fluid in the blood)
Food craving

60+:

Arthritis (form of joint disorder that involves inflammation of one or more joints)
Abdominal distension
Meningitis bacterial (bacterial inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges)
Back pain
Blood cholesterol increased
Blood triglycerides increased
Globulins decreased
Glomerular filtration rate decreased
Low density lipoprotein increased (cholesterol increased in blood)
Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve)

What are the existing conditions these people have? *

Hypopituitarism (diminished hormone secretion by the pituitary gland, causing dwarfism in children and premature aging in adults): 16 people, 26.23%
Depression: 8 people, 13.11%
Essential Hypertension (primary hypertension): 6 people, 9.84%
Blood Thyroid Stimulating Hormone Decreased: 5 people, 8.20%
Blood Corticotrophin Decreased: 5 people, 8.20%
Asthma: 5 people, 8.20%
Thyroid Diseases: 4 people, 6.56%
Pulmonary Embolism (blockage of the main artery of the lung): 4 people, 6.56%
Fluid Retention (an abnormal accumulation of fluid in the blood): 4 people, 6.56%
Blood Pressure Abnormal: 4 people, 6.56%

* Approximation only. Some reports may have incomplete information.

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