Gentamicin sulfate and Doxycycline drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Gentamicin sulfate (gentamicin sulfate) and Doxycycline (doxycycline hyclate). Common drug interactions include weight decreased among females and renal failure among males.

The phase IV clinical study analyzes what interactions people have when they take Gentamicin sulfate and Doxycycline. It is created by eHealthMe based on reports of 75 people who take the same drugs from the FDA, and is updated regularly.

What is Gentamicin sulfate?

Gentamicin sulfate has active ingredients of gentamicin sulfate. It is often used in urinary tract infection. eHealthMe is studying from 3,942 Gentamicin sulfate users. Check the latest studies of Gentamicin sulfate.

What is Doxycycline?

Doxycycline has active ingredients of doxycycline hyclate. It is often used in acne. eHealthMe is studying from 60,868 Doxycycline users. Check the latest studies of Doxycycline.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 17, 2026

75 people who take Gentamicin sulfate and Doxycycline together, and have interactions are studied.

Gentamicin sulfate and Doxycycline drug interactions.

What are the common drug interactions of Gentamicin Sulfate and Doxycycline, by gender? *:

female:

Weight decreased
Abscess neck (neck abscesses)
Addison's disease (addison's disease, a hormonal disorder disease)
Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
Anaemia of chronic disease
Arterial occlusive disease (slow process through which arteries throughout the body become progressively narrowed and eventually completely blocked)
Arteriovenous fistula site complication
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Bone disorder
Candidiasis (candidiasis or thrush is a fungal infection)

male:

Renal failure (kidney dysfunction)
Chronic kidney disease
Neuropathy peripheral (surface nerve damage)
Swelling face
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Abdominal pain upper
Activated partial thromboplastin time prolonged
Alanine aminotransferase increased
Aspartate aminotransferase increased
Bilirubin conjugated increased

What are the common drug interactions of Gentamicin Sulfate and Doxycycline, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Abscess of eyelid
Colitis (inflammation of colon)
Nasopharyngitis (inflammation of the nasopharynx)
Oropharyngeal pain
Rash
Staphylococcal infection (an infection with staphylococcus bacteria)

20-29:

Hyperaldosteronism
Anxiety
Cholecystitis chronic (long lasting infection of gallbladder)
Emotional disorder
Gallbladder disorder
Injury
Pain
Psychological trauma
Pulmonary embolism (blockage of the main artery of the lung)
Alanine aminotransferase increased

30-39:

Renal failure (kidney dysfunction)
Chronic kidney disease
Depression
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Abdominal pain upper
Activated partial thromboplastin time prolonged
Alanine aminotransferase increased
Aspartate aminotransferase increased
Bilirubin conjugated increased
Blood alkaline phosphatase increased

40-49:

Abdominal pain
Aggression
Arthropathy
Autoimmune disorder (a condition in which the immune system attacks the body's normal substances and tissue)
Back pain
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
Depression
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Drug hypersensitivity
Enterococcal sepsis

50-59:

Candidiasis (candidiasis or thrush is a fungal infection)
Cardiac arrest
Cardiomegaly (increased size of heart than normal)
Cardiovascular disorder (heart diseases)
Cataract (clouding of the lens inside the eye)
Cellulitis (infection under the skin)
Coagulopathy (blood's ability to clot is impaired)
Contusion (a type of hematoma of tissue in which capillaries)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Deafness

60+:

Cataract (clouding of the lens inside the eye)
Malaise (a feeling of general discomfort or uneasiness)
Addison's disease (addison's disease, a hormonal disorder disease)
Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
Anaemia of chronic disease
Aneurysm (enlargement of an artery caused by a weakening of the artery wall)
Aortic arteriosclerosis (hardening of the aortic arteries)
Aortic dilatation
Arterial occlusive disease (slow process through which arteries throughout the body become progressively narrowed and eventually completely blocked)
Arteriovenous fistula site complication

What are the existing conditions these people have? *

Pain: 15 people, 20.00%
High Blood Pressure: 13 people, 17.33%
Multiple Myeloma (cancer of the plasma cells): 12 people, 16.00%
Hypercalcaemia Of Malignancy (elevated calcium (ca+) level in the blood with cancer): 7 people, 9.33%
Stress And Anxiety: 7 people, 9.33%
High Blood Cholesterol: 7 people, 9.33%
Depression: 7 people, 9.33%
Pneumonia: 7 people, 9.33%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 8.00%
Asthma: 6 people, 8.00%

* Approximation only. Some reports may have incomplete information.

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