Gentamicin and Amikin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Gentamicin (gentamicin sulfate) and Amikin (amikacin sulfate). Common drug interactions include agranulocytosis among females and agranulocytosis among males.

The phase IV clinical study analyzes what interactions people have when they take Gentamicin and Amikin. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Gentamicin?

Gentamicin has active ingredients of gentamicin sulfate. It is often used in urinary tract infection. eHealthMe is studying from 21,654 Gentamicin users. Check the latest studies of Gentamicin.

What is Amikin?

Amikin has active ingredients of amikacin sulfate. eHealthMe is studying from 528 Amikin users. Check the latest studies of Amikin.

On Jul, 16, 2026

19 people who take Gentamicin and Amikin together, and have interactions are studied.

Gentamicin and Amikin drug interactions.

What are the common drug interactions of Gentamicin and Amikin, by gender? *:

female:

Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
Acute circulatory failure (shock)
Cardiac arrest
Hypertonia (abnormal increase in muscle tension and a reduced ability of a muscle to stretch)
Sepsis (a severe blood infection that can lead to organ failure and death)
Thrombocytopenia (decrease of platelets in blood)
Anaemia (lack of blood)
Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
Endometritis (inflammation of the endometrium)
Excessive bronchial secretion

male:

Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
Drug rash with eosinophilia and systemic symptoms (adverse drug reactions with rash)
Eosinophilia (eosinophil count in the peripheral blood exceeds)
Gastritis (inflammation of stomach)
Grand mal convulsion (a type of generalized seizure that affects the entire brain)
Neutropenia (an abnormally low number of neutrophils)
Proteinuria (presence of protein in the urine)
Rash
Renal failure acute (rapid kidney dysfunction)
Systemic inflammatory response syndrome (an inflammatory state affecting the whole body, frequently a response of the immune system to infection)

What are the common drug interactions of Gentamicin and Amikin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
Acute circulatory failure (shock)
Cardiac arrest
Hypertonia (abnormal increase in muscle tension and a reduced ability of a muscle to stretch)
Sepsis (a severe blood infection that can lead to organ failure and death)
Thrombocytopenia (decrease of platelets in blood)
Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
Endometritis (inflammation of the endometrium)
Excessive bronchial secretion

30-39:

Thrombocytopenia (decrease of platelets in blood)

40-49:

Pyrexia (fever)
Gastritis (inflammation of stomach)
Systemic inflammatory response syndrome (an inflammatory state affecting the whole body, frequently a response of the immune system to infection)

50-59:

Drug rash with eosinophilia and systemic symptoms (adverse drug reactions with rash)
Skin test positive
Flushing (the warm, red condition of human skin)
Pyrexia (fever)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
Diabetes mellitus inadequate control
Renal failure acute (rapid kidney dysfunction)

60+:

Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
Anaemia (lack of blood)
Red blood cell count decreased
Dermatitis bullous (inflammation of the skin characterized by the presence of bullae which are filled with fluid)
Drug rash with eosinophilia and systemic symptoms (adverse drug reactions with rash)
Eosinophilia (eosinophil count in the peripheral blood exceeds)
Grand mal convulsion (a type of generalized seizure that affects the entire brain)
Haematoma (collection of blood outside the blood vessels)
Neutropenia (an abnormally low number of neutrophils)
Proteinuria (presence of protein in the urine)

What are the existing conditions these people have? *

Candidiasis (candidiasis or thrush is a fungal infection): 2 people, 10.53%
Prostatic Adenoma (prostatic non-cancerous tumour): 1 person, 5.26%
Pneumonia Staphylococcal (pneumonia staphylococcal infections are usually caused by the organism staphylococcus aureus): 1 person, 5.26%
Pancreatic Insufficiency: 1 person, 5.26%
Increased Bronchial Secretion: 1 person, 5.26%
Hypersensitivity: 1 person, 5.26%
High Blood Pressure: 1 person, 5.26%
Depression: 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

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