Gentamicin and Plaquenil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Gentamicin (gentamicin sulfate) and Plaquenil (hydroxychloroquine sulfate). Common drug interactions include weight decreased among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Gentamicin and Plaquenil. It is created by eHealthMe based on reports of 49 people who take the same drugs from the FDA, and is updated regularly.

What is Gentamicin?

Gentamicin has active ingredients of gentamicin sulfate. It is often used in urinary tract infection. eHealthMe is studying from 21,654 Gentamicin users. Check the latest studies of Gentamicin.

What is Plaquenil?

Plaquenil has active ingredients of hydroxychloroquine sulfate. It is often used in systemic lupus erythematosus. eHealthMe is studying from 91,019 Plaquenil users. Check the latest studies of Plaquenil.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

49 people who take Gentamicin and Plaquenil together, and have interactions are studied.

Gentamicin and Plaquenil drug interactions.

What are the common drug interactions of Gentamicin and Plaquenil, by gender? *:

female:

Weight decreased
Anxiety
Asthenia (weakness)
Cataract (clouding of the lens inside the eye)
Death
Epistaxis (bleed from the nose)
Haemarthrosis (haemarthrosis is where blood is able to enter the joint capsule)
Hypotension (abnormally low blood pressure)
Injury
Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)

male:

Anxiety
Depression
Asthenia (weakness)
Decreased appetite
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
Drug abuser
Drug dependence
Drug ineffective
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Erectile dysfunction

What are the common drug interactions of Gentamicin and Plaquenil, by age (0-1 to 60+)? *:

0-1:

Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Foetal growth restriction (poor growth of a baby while in the mother's womb during pregnancy)
Hypoxia (low oxygen in tissues)
Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
Maternal exposure before pregnancy (use of substance before pregnancy)
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Respiratory distress (difficulty in breathing)

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Abdominal distension
Abdominal pain
Alopecia (absence of hair from areas of the body)
Angioedema (rapid swelling of the dermis)
Anxiety
Asthenia (weakness)
Blood immunoglobulin e decreased
Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
Chronic fatigue syndrome (disorder that causes extreme fatigue)
Decreased appetite

40-49:

Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Synovitis (inflammation of the synovial membrane)
Back injury
Dehydration (dryness resulting from the removal of water)
Gastroenteritis (inflammation of stomach and intestine)
Delirium (wild excitement)
Diarrhoea
Drug addiction
Laceration (tearing of soft body tissue)
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)

50-59:

Cardiac failure congestive

60+:

Chronic kidney disease
Malaise (a feeling of general discomfort or uneasiness)
Cardiomyopathy (weakening of the heart muscle)
Death
Dizziness
Dysphagia (a condition in which swallowing is difficult or painful)
Epistaxis (bleed from the nose)
Eye disorder
Fatigue (feeling of tiredness)
Haemarthrosis (haemarthrosis is where blood is able to enter the joint capsule)

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 7 people, 14.29%
Sleep Disorder: 5 people, 10.20%
Pain: 5 people, 10.20%
Lung Disorder (lung disease): 4 people, 8.16%
High Blood Pressure: 4 people, 8.16%
Haemostasis (stopping of bleeding): 4 people, 8.16%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 8.16%
Infection: 3 people, 6.12%
Cardiac Disorder: 3 people, 6.12%
Acute Coronary Syndrome (acute chest pain and other symptoms that happen because the heart does not get blood): 3 people, 6.12%

* Approximation only. Some reports may have incomplete information.

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