Genvoya and Baclofen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Genvoya (cobicistat; elvitegravir; emtricitabine; tenofovir alafenamide fumarate) and Baclofen (baclofen). Common drug interactions include multiple fractures among females and emotional distress among males.

The phase IV clinical study analyzes what interactions people have when they take Genvoya and Baclofen. It is created by eHealthMe based on reports of 73 people who take the same drugs from the FDA, and is updated regularly.

What is Genvoya?

Genvoya has active ingredients of cobicistat; elvitegravir; emtricitabine; tenofovir alafenamide fumarate. It is often used in hiv infection. eHealthMe is studying from 13,538 Genvoya users. Check the latest studies of Genvoya.

What is Baclofen?

Baclofen has active ingredients of baclofen. It is often used in muscle spasms. eHealthMe is studying from 108,664 Baclofen users. Check the latest studies of Baclofen.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 03, 2026

73 people who take Genvoya and Baclofen together, and have interactions are studied.

Genvoya and Baclofen drug interactions.

What are the common drug interactions of Genvoya and Baclofen, by gender? *:

female:

  1. Multiple fractures
  2. Osteopenia (a condition where bone mineral density is lower than normal)
  3. Back pain
  4. Gait disturbance
  5. Skeletal injury (bone and supporting muscle injury)
  6. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  7. Bone disorder
  8. Bone loss
  9. Drug ineffective
  10. Exostosis (formation of new bone on the surface of a bone)

male:

  1. Emotional distress
  2. Pain
  3. Blood creatinine increased
  4. Foot fracture
  5. Mobility decreased (ability to move is reduced)
  6. Gait disturbance
  7. Hip arthroplasty
  8. Intervertebral disc degeneration (spinal disc degeneration)
  9. Multiple fractures
  10. Renal impairment (severely reduced kidney function)

What are the common drug interactions of Genvoya and Baclofen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Emotional distress
  4. Pain
  5. Bone density decreased
  6. Depression
  7. Renal failure (kidney dysfunction)
  8. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  9. Nephrolithiasis (calculi in the kidneys)
  10. Osteoarthritis (a joint disease caused by cartilage loss in a joint)

40-49:

  1. Foot fracture
  2. Fractured sacrum
  3. General physical health deterioration (weak health status)
  4. Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
  5. Nephropathy (damage to or disease of a kidney)
  6. Psychiatric symptom
  7. Quality of life decreased
  8. Renal atrophy (wasting of kidney)
  9. Rib fracture
  10. Skeletal injury (bone and supporting muscle injury)

50-59:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Emotional distress
  3. Pain
  4. Chronic kidney disease
  5. Anxiety
  6. Osteoporosis (bones weak and more likely to break)
  7. Bone density decreased
  8. Depression
  9. Osteopenia (a condition where bone mineral density is lower than normal)
  10. Renal failure (kidney dysfunction)

60+:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Fanconi syndrome acquired (self developed genetic disease of kidney damage due to defective transport system)
  4. Lumbar vertebral fracture
  5. Malaise (a feeling of general discomfort or uneasiness)
  6. Multiple fractures
  7. Nephropathy (damage to or disease of a kidney)
  8. Osteoporosis (bones weak and more likely to break)
  9. Parkinson's disease
  10. Radiculopathy (a set of conditions in which one or more nerves is affected and does not work properly)

What are the existing conditions these people have? *

  1. Pain: 13 people, 17.81%
  2. Stress And Anxiety: 12 people, 16.44%
  3. Depression: 12 people, 16.44%
  4. Hypersensitivity: 10 people, 13.70%
  5. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 9 people, 12.33%
  6. High Blood Pressure: 9 people, 12.33%
  7. Nausea (feeling of having an urge to vomit): 7 people, 9.59%
  8. Bacterial Infection: 6 people, 8.22%
  9. Fungal Infection: 6 people, 8.22%
  10. Viral Infection: 6 people, 8.22%

* Approximation only. Some reports may have incomplete information.

Do you take Genvoya and Baclofen?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Genvoya and Baclofen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Genvoya:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Baclofen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Genvoya and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Baclofen and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on cobicistat; elvitegravir; emtricitabine; tenofovir alafenamide fumarate and baclofen (the active ingredients of Genvoya and Baclofen, respectively), and Genvoya and Baclofen (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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