Genvoya and Lactulose drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Genvoya (cobicistat; elvitegravir; emtricitabine; tenofovir alafenamide fumarate) and Lactulose (lactulose). Common drug interactions include anhedonia among females and pain among males.

The phase IV clinical study analyzes what interactions people have when they take Genvoya and Lactulose. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Genvoya?

Genvoya has active ingredients of cobicistat; elvitegravir; emtricitabine; tenofovir alafenamide fumarate. It is often used in hiv infection. eHealthMe is studying from 13,538 Genvoya users. Check the latest studies of Genvoya.

What is Lactulose?

Lactulose has active ingredients of lactulose. It is often used in constipation. eHealthMe is studying from 46,960 Lactulose users. Check the latest studies of Lactulose.



On Jul, 27, 2026

20 people who take Genvoya and Lactulose together, and have interactions are studied.

Genvoya and Lactulose drug interactions.

What are the common drug interactions of Genvoya and Lactulose, by gender? *:

female:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Emotional distress
  3. Pain
  4. Osteoporosis (bones weak and more likely to break)
  5. Anxiety
  6. Chronic kidney disease
  7. Bone density decreased
  8. Multiple fractures
  9. Quality of life decreased
  10. Renal injury (kidney injury)

male:

  1. Pain
  2. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  3. Memory impairment
  4. Mobility decreased (ability to move is reduced)
  5. Nightmare (unpleasant dream)
  6. Osteoporosis (bones weak and more likely to break)
  7. Pulmonary embolism (blockage of the main artery of the lung)
  8. Quality of life decreased
  9. Renal failure (kidney dysfunction)
  10. Renal impairment (severely reduced kidney function)

What are the common drug interactions of Genvoya and Lactulose, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Decreased activity
  4. Emotional distress
  5. Fatigue (feeling of tiredness)
  6. Loss of employment
  7. Mobility decreased (ability to move is reduced)
  8. Pain
  9. Quality of life decreased
  10. Social problem

40-49:

n/a

50-59:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Emotional distress
  3. Osteoporosis (bones weak and more likely to break)
  4. Pain
  5. Bone density decreased
  6. Chronic kidney disease
  7. Anxiety
  8. Blood creatinine increased
  9. Lower limb fracture
  10. Renal impairment (severely reduced kidney function)

60+:

  1. Pain
  2. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  3. Memory impairment
  4. Multiple fractures
  5. Nightmare (unpleasant dream)
  6. Pulmonary embolism (blockage of the main artery of the lung)
  7. Quality of life decreased
  8. Renal failure (kidney dysfunction)
  9. Renal injury (kidney injury)
  10. Adverse event

What are the existing conditions these people have? *

  1. Depression: 6 people, 30.00%
  2. Stress And Anxiety: 6 people, 30.00%
  3. High Blood Cholesterol: 6 people, 30.00%
  4. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 30.00%
  5. Pain: 6 people, 30.00%
  6. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 4 people, 20.00%
  7. Hypovitaminosis (any of several diseases caused by deficiency of one or more vitamins): 4 people, 20.00%
  8. Viral Infection: 4 people, 20.00%
  9. High Blood Pressure: 4 people, 20.00%
  10. Gastric Ulcer (stomach ulcer): 4 people, 20.00%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Genvoya and Lactulose:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Genvoya:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Lactulose:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Genvoya and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lactulose and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on cobicistat; elvitegravir; emtricitabine; tenofovir alafenamide fumarate and lactulose (the active ingredients of Genvoya and Lactulose, respectively), and Genvoya and Lactulose (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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