Genvoya and Renvela drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Genvoya (cobicistat; elvitegravir; emtricitabine; tenofovir alafenamide fumarate) and Renvela (sevelamer carbonate). Common drug interactions include anxiety among females and anhedonia among males.

The phase IV clinical study analyzes what interactions people have when they take Genvoya and Renvela. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Genvoya?

Genvoya has active ingredients of cobicistat; elvitegravir; emtricitabine; tenofovir alafenamide fumarate. It is often used in hiv infection. eHealthMe is studying from 13,538 Genvoya users. Check the latest studies of Genvoya.

What is Renvela?

Renvela has active ingredients of sevelamer carbonate. eHealthMe is studying from 10,923 Renvela users. Check the latest studies of Renvela.

On Aug, 11, 2026

18 people who take Genvoya and Renvela together, and have interactions are studied.

What are the common drug interactions of Genvoya and Renvela, by gender? *:

female:

Anxiety
Emotional distress
Pain
Renal failure (kidney dysfunction)
Chronic kidney disease
Blood creatinine increased
Skeletal injury (bone and supporting muscle injury)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Depression
Fatigue (feeling of tiredness)

male:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Chronic kidney disease
Osteoporosis (bones weak and more likely to break)
Renal tubular necrosis (death of kidney tubules)
Nephropathy (damage to or disease of a kidney)
Fatigue (feeling of tiredness)
Foot fracture
Hepatitis c
Hypertension (high blood pressure)
Pneumonia

What are the common drug interactions of Genvoya and Renvela, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Anxiety
Chronic kidney disease
Emotional distress
Pain
Depression
Nephrogenic anaemia (anaemia due to kidney disease)
Osteoporosis (bones weak and more likely to break)
Renal failure (kidney dysfunction)
Skeletal injury (bone and supporting muscle injury)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)

40-49:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Blood creatinine increased
Emotional distress
Fatigue (feeling of tiredness)
Pain
Chronic kidney disease
Renal disorder (kidney disease)
Renal failure (kidney dysfunction)
Renal injury (kidney injury)

50-59:

Pain
Osteoporosis (bones weak and more likely to break)
Renal failure (kidney dysfunction)
Renal tubular necrosis (death of kidney tubules)
Bone density decreased
Foot fracture
Antisocial behaviour
Death
Depression
Dyspnoea (difficult or laboured respiration)

60+:

Anaemia (lack of blood)
Chronic kidney disease
Hepatitis c
Hyperkalaemia (damage to or disease of the kidney)
Hypertension (high blood pressure)
Renal failure (kidney dysfunction)

What are the existing conditions these people have? *

High Blood Pressure: 4 people, 22.22%
Genital Herpes (herpes infection of genital): 3 people, 16.67%
Cough: 3 people, 16.67%
Arrhythmias (irregular heartbeat): 3 people, 16.67%
Pain: 3 people, 16.67%
Oropharyngeal Pain: 3 people, 16.67%
Asthma: 3 people, 16.67%
Nasopharyngitis (inflammation of the nasopharynx): 3 people, 16.67%
Inflammation: 3 people, 16.67%
Infection: 3 people, 16.67%

* Approximation only. Some reports may have incomplete information.

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